Development and validation of motion artefact rejection system (mars) for electrocardiography using novel skin-stretch estimation approach

Publication date: Available online 2 December 2019Source: Sensors and Actuators A: PhysicalAuthor(s): Anubha Kalra, Andrew LoweAbstractElectrocardiography (ECG) is widely used in clinical practice, for example to diagnose coronary artery disease or the cause of chest pain during a stress test, while the patient is running on a treadmill. However, artefacts due to subject’s movement are hard to identify and eliminate and can be easily mistaken for symptoms of arrhythmia, leading to misdiagnosis and false alarms. Skin stretch has been identified as a major source of motion artefacts in ECG signals.A Motion Artefact Rejection System (MARS) has been developed, where a polymer patch electrode with Young’s modulus lower than of skin was used to simultaneously measure ECG and skin stretch. Skin-stretch artefacts were induced in 7 subjects across the following age groups: 18–35 years (3 subjects), 36–55 years (2 subjects), and 56 years and above (2 subjects). The motion artefact measured using patch electrodes was used in advanced signals processing algorithms- Principal Component Analysis (PCA) and Independent Component Analysis (ICA).A novel, state-of-the-art technique to identify and eliminate motion artefacts from ECG signals has been developed which is feasible for medical implementations.Graphical abstract
Source: Sensors and Actuators A: Physical - Category: Physics Source Type: research

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Publication date: January 2020Source: Archives of Cardiovascular Diseases Supplements, Volume 12, Issue 1Author(s): M. Drissa, H. Jamila, H. DrissaBackgroundAtrial septal defect (ASD) is one of the most common causes of congenital heart disease manifested in adulthood and a subgroup of patients may not develop symptoms until late adulthood.Aim of studyThe aim of our study was to describe clinical and likelihood picture of adults over 60 years born with an ASD type II.MethodsWe performed a retrospective analysis of adult's ASD referred to our institution from 2010 through 2018. Clinical, electrocardiographic, echocardiograp...
Source: Archives of Cardiovascular Diseases Supplements - Category: Cardiology Source Type: research
Conclusion: To our knowledge, this case is the first report of severe drug-refractory vasospastic angina triggered by pregnancy. The hormonal and nervous system changes that occur during pregnancy appear to be a trigger for vasospasm, further highlighted by the quick resolution of the patient's symptoms postdelivery. A multidisciplinary approach for treatment of both mother and baby was necessary. Our case provides a cautionary tale that patients with refractory vasospastic angina may want to pursue definitive contraception. PMID: 31903064 [PubMed]
Source: Ochsner Journal - Category: General Medicine Tags: Ochsner J Source Type: research
A 60-something male was sent from Dialysis for several days of SOB.  He did not know his medical history well.The patient was in no distress.The paramedics recorded an ECG:Here I magnify the limb leads and precordial leads:Now of course you see the convex ST elevation in V3 and V4, and the STE in V2 that is preceded by a spike. Is this STEMI?Here is the Computer Interpretation:The medics activated the cath lab.  Do you agree? I was in the ED, and whenever I hear that there has been a prehospital cath lab activation, I like to go take a look because there are many false positive activations, es...
Source: Dr. Smith's ECG Blog - Category: Cardiology Authors: Source Type: blogs
AliveCor is close to our hearts. Literally. David Albert, the co-founder of the company, started experimenting with handheld, wireless ECG devices in the late 90s. Approximately 10 years later we tried out their FDA-cleared, medical grade gadget. It was a truly inspiring moment. Needless to say, we’ve been keeping track of their journey ever since. In our eyes Kardia is the textbook example of technology shaping health care, empowering and supporting not only e-patients, but medical professionals as well. So, let’s take a look at their newest creation, the KardiaMobile6L! Why did the chicken cross the ro...
Source: The Medical Futurist - Category: Information Technology Authors: Tags: Health Sensors & Trackers cardiology ecg fda Healthcare heart technology Source Type: blogs
Conclusion of this paper: Fever is a great risk factor for arrhythmia events in Brugada Syndrome patients. Patients with known fever-triggered Brugada syndrome should be surveilled closely during fever and be started on antipyretic therapy as soon as possible.  There are limited data regarding the impact of EP study in BrS patients triggered by fever.  An EP study might be helpful in symptomatic patients (Sroubek et al., 2016) in the presence of spontaneous BrS ECG or drug-induced ECG.The prognostic significance of fever-induced Brugada syndrome.  Heart Rhythm 2016.Eighty-eight asymptomatic patient...
Source: Dr. Smith's ECG Blog - Category: Cardiology Authors: Source Type: blogs
ConclusionsThe findings suggested that small or modest doses of methadone could exert dose-dependent effects on cardiac repolarization in cancer patients.Trial RegistrationUMIN Clinical Trials Registry, UMIN000034519.
Source: Cardiology and Therapy - Category: Cardiology Source Type: research
Written by Pendell Meyers, submitted by Siva Vittozzi-WongA man in his 30s with history of hypertension, hyperlipidemia, and diabetes presented with chest pain which started 12 hours prior to presentation. The pain was described as pressure, constant for 12 hours, radiating to the jaw, with left arm numbness. Initial vitals were significant for bradycardia at 45 beats per minute.Here is his presenting ECG with active pain:What do you think?Here was the prior EKG on file:The emergency medicine resident (who has received lectures from me on hyperacute T-waves, suble OMI, etc) documented the following interpretation:" In...
Source: Dr. Smith's ECG Blog - Category: Cardiology Authors: Source Type: blogs
Written by Meyers, edits by SmithA 50-ish year old man was working construction when he suddenly collapsed. Coworkers started CPR within 1 minute of collapse. EMS arrived within 10 minutes and continued CPR and ACLS, noting alternating asystole and sinus bradycardia during rhythm checks. He received various ACLS medications and arrived at the ED with a perfusing rhythm.Initial vitals included heart rate around 100 bpm and BP 174/96. Here is his initial ECG, very soon after ROSC:What do you think?Sinus tachycardia.  There is incomplete RBBB (QRS duration less than 120 ms).  There is diffuse STD, maximal in V4-V5 a...
Source: Dr. Smith's ECG Blog - Category: Cardiology Authors: Source Type: blogs
We report an uncommon case of myocarditis complicated with permanent CAVB caused by Escherichia coli (E coli) bacteremia. Patient concerns: A 77-year-old woman presented at the emergency department with chest pain, dizziness, nausea, and cold sweats of 1-day duration. She had histories of type 2 diabetes mellitus, hyperlipidemia, and chronic kidney disease with regular medical therapy. Diagnosis: Both blood and urine cultures were positive for E coli. Regional inferior wall motion abnormalities on echocardiography, unexplained life-threatening arrhythmias, newly abnormal electrocardiogram, elevated cardiac troponins,...
Source: Medicine - Category: Internal Medicine Tags: Research Article: Clinical Case Report Source Type: research
ConclusionsA high incidence of CV events, with no apparent correlation with CV comorbidities or risk factors, was observed. Prompt identification and treatment of CV events allowed most pts to complete the treatment with FP.Clinical trial identificationNCT02665312.Legal entity responsible for the studyThe authors.FundingHas not received any funding.DisclosureM. Aglietta: Advisory / Consultancy: Bristol-Myers Squibb; Advisory / Consultancy: Merck; Advisory / Consultancy: Roche. All other authors have declared no conflicts of interest.
Source: Annals of Oncology - Category: Cancer & Oncology Source Type: research
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