Diagnostic accuracy of fetal MRI to detect cleft palate: a meta-analysis

Conclusion: This meta-analysis shows that MRI has an excellent sensitivity and good to excellent specificity for diagnosing cleft palate in fetuses at risk for orofacial clefts. Future research should assess applicability for clinical care.What is Known:•Using ultrasound for prenatal detection of cleft palate leads to misdiagnosis frequently.•MRI could potentially improve the prenatal detection rate of cleft palate.What is New:•Eight studies describe the diagnostic accuracy of MRI for detecting cleft palate.•Combined results show excellent sensitivity and good to excellent specificity.
Source: European Journal of Pediatrics - Category: Pediatrics Source Type: research