Atypical presentation of classic Kaposi sarcoma in circumcised penis presenting as an ulcerative nodule with human herpesvirus 8 (HHV8) positivity and successfully treated with only local excision

Although the Kaposi sarcoma (KS) is one of the AIDS defining entity and seen in almost one third of HIV infected patients with low CD4 cell counts, it is not uncommon in HIV seronegative persons, but genital K...
Source: Infectious Agents and Cancer - Category: Cancer & Oncology Authors: Tags: Short Report Source Type: research

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Thank you, for providing me with the opportunity  to respond to Dr Grant’s Letter to the Editor regarding: Preserving Pulmonary Function: A Palliative Approach published in the September 2019 issue of The Journal for Nurse Practitioner. Dr. Grant is on-target and not only following recommendations for earlier palliative interventions for cancer patients by the American Society of Oncologists (ASCO) and the National Comprehensive Cancer Network (NCCN). Equally important to recognize is the National Quality Forum (NQF) who serve as the gold standard for patient outcome measurements in the U.S.
Source: The Journal for Nurse Practitioners - Category: Nursing Authors: Tags: Letter to the Editor Source Type: research
Authors: Koyama N, Aoshiba K, Nakamura H Abstract The aim of this study was to assess the association of serum C-reactive protein (CRP) levels with outcomes in 81 patients with epidermal growth factor receptor (EGFR)-mutated non-small cell lung cancer (NSCLC). Patients with high serum CRP levels had lower therapeutic responses to EGFR-tyrosine kinase inhibitors (43.8%), and shorter time to treatment failure (TTF; 5.8 months) and overall survival (OS; 14.2 months) than those with low CRP levels. In multivariate analysis, serum CRP level was associated with TTF (hazard ratio [HR] 4.86) and OS (HR 49.42). High serum C...
Source: Cancer Investigation - Category: Cancer & Oncology Tags: Cancer Invest Source Type: research
Authors: Sher AF, Golshani GM, Wu S Abstract Background: Pembrolizumab as an immune checkpoint inhibitor (ICI) has emerged as an effective treatment for many cancers. It has unique immune related adverse events and little is known about its risk of fatal adverse events (FAE). We conducted a meta-analysis of clinical trials to determine the incidence and risk of fatal adverse events with pembrolizumab.Methods: A systematic search for phase I-III clinical trials of pembrolizumab was conducted using databases including PUBMED, and abstracts presented at the American Society of Clinical Oncology (ASCO) conferences unti...
Source: Cancer Investigation - Category: Cancer & Oncology Tags: Cancer Invest Source Type: research
[Nation] Young people with innovative ideas to reduce HIV infections among adolescents will receive cash incentives to showcase best practices to fight the deadly virus during an international conference in Kisumu.
Source: AllAfrica News: HIV-Aids and STDs - Category: Infectious Diseases Source Type: news
Publication date: Available online 27 January 2020Source: Mutation Research/Fundamental and Molecular Mechanisms of MutagenesisAuthor(s): Samuel Buxton, Yvonne Voges, Claudia Donath, Adriana OllerAbstractNickel metal is a naturally occurring element used in many industrial and consumer applications. Human epidemiological data and animal cancer bioassays indicate that nickel metal is not likely to be a human carcinogen. Yet, nickel metal is classified as a suspected human carcinogen (CLP) and possibly carcinogenic to humans (IARC). There are no reliable studies on the potential for nickel metal to induce gene and micronucle...
Source: Mutation Research Fundamental and Molecular Mechanisms of Mutagenesis - Category: Cytology Source Type: research
A new study from New York University Grossman School of Medicine has found that cancer patients who took one dose of psilocybin had more positive feelings and less death anxiety.
Source: the Mail online | Health - Category: Consumer Health News Source Type: news
(University of South Florida (USF Health)) A study led by researchers at the University of South Florida Morsani College of Medicine discovered that three major proinflammatory mediators -- interlukin-1 beta, tumor necrosis factor alpha, and thrombin -- individually and especially when combined, directly drive capillary loss known to occur in diseases such as hypertension, diabetes, cardiovascular diseases, neurodegenerative diseases and malignant cancer. Using an innnovative 3-D cell model, the investigators also identified combinations of existing drugs that can block the regression of these tiny blood vessels.
Source: EurekAlert! - Cancer - Category: Cancer & Oncology Source Type: news
Sensitive and selective SERS probe for detecting the activity of γ-glutamyl transpeptidase in serum. Anal Chim Acta. 2020 Feb 22;1099:119-125 Authors: Jiang L, Guo D, Wang L, Chang S, Li JB, Zhan DS, Fodjo EK, Gu HX, Li DW Abstract γ-Glutamyl transpeptidase (GGT) has attracted considerable attention for its regulatory effect on glutathione metabolism in living organisms; further, its close relationship with physiological dysfunctions such as hepatitis and liver cancers has enhanced its applicability. Therefore, the accurate detection of GGT levels is particularly important for the early di...
Source: Analytica Chimica Acta - Category: Chemistry Authors: Tags: Anal Chim Acta Source Type: research
Publication date: Available online 21 September 2018Source: The Lancet HIVAuthor(s): Nancy A Hessol, Hannah Whittemore, Eric Vittinghoff, Ling C Hsu, Danning Ma, Susan Scheer, Sandra K SchwarczSummaryBackgroundCancer survivors are at increased risk for subsequent primary cancers. People living with HIV are at increased risk for AIDS-defining and non-AIDS-defining cancers, but little is known about their risk of first versus second primary cancers. We identified first and second primary cancers that occurred in above population expected numbers among people diagnosed with HIV in San Francisco, and compared first and second ...
Source: The Lancet HIV - Category: Infectious Diseases Source Type: research
Certain cancers - - ALL and cancers of the tongue, penis - - becoming more common
Source: The Doctors Lounge - Oncology - Category: Cancer & Oncology Tags: Dermatology, Infections, AIDS, Internal Medicine, Oncology, Pathology, Pharmacy, Journal, Source Type: news
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