Alternative Effective and Safe Induction Regimens for Newly Diagnosed Acute Myeloid Leukemia in Patients with Cardiac Contra-indication to Anthracyclines

Conclusion: TA, FLAG and CLARA regimens are efficient and associated with acceptable toxicity in AML patients ineligible for "3+7" regimen due to cardiac comorbidities. However, long term outcome remains disappointing highlighting the need for the development of less toxic regimens.
Source: Clinical Lymphoma Myeloma and Leukemia - Category: Cancer & Oncology Source Type: research