Incidence of severe urinary tract infections not increased by initiating sodium ‐glucose cotransporter‐2 inhibitors

AbstractRecently, the Food and Drug Administration (FDA) issued an advisory that sodium ‐glucose cotransporter‐2 (SGLT‐2) inhibitors are associated with a risk of severe urinary tract infection (UTI) (1). They reported 19 patients with life‐threatening sepsis due to UTI and severe pyelonephritis after initiating SGLT‐2 inhibitors who required hospitalization. Some of them req uired admission to an intensive care unit or dialysis in order to treat acute renal failure.
Source: Journal of Diabetes Investigation - Category: Endocrinology Authors: Tags: Commentary Source Type: research

Related Links:

New research finds that girls with autoimmune hypothyroidism show reduced brown adipose tissue activation in response to cold stimulation.Journal of the Endocrine Society
Source: Medscape Today Headlines - Category: Consumer Health News Tags: Diabetes & Endocrinology Journal Article Source Type: news
Is single gland excision a viable option for the treatment of MEN1-associated primary hyperparathyroidism? How does it compare with other treatment methods?Clinical Endocrinology
Source: Medscape Today Headlines - Category: Consumer Health News Tags: Diabetes & Endocrinology Journal Article Source Type: news
TYPE 2 diabetes is a common condition yet many people in the UK will not realise they have it because the symptoms do not necessarily make you feel unwell. Symptoms are caused by consistently high blood sugar levels, and, overtime, this can affect different parts of the body, including the shoulder.
Source: Daily Express - Health - Category: Consumer Health News Source Type: news
You are leaving AARP.org and going to the website of our trusted provider. ... The provider ’s terms, conditions and policies apply. ... Please return to AARP.org to learn more about other benefits.
Source: AARP.org News - Category: American Health Source Type: news
Publication date: Available online 8 January 2020Source: Nano EnergyAuthor(s): Hong Yin, Wangqiang Shen, Hong-Qing Qu, Chong Li, Ming-Qiang ZhuAbstractTo improve the electronic conductivity and accelerate the Na-ion diffusion in active materials for sodium-ion batteries (SIBs), Sb2Te3-Te nano-heterostructure (STNH) electrodes are constructed based on the hierarchical nanostructures of two-dimensional (2D) Sb2Te3 nanoblades serialized by one-dimensional (1D) Te nanowires for high-performance anode material. The STNH electrode can deliver high sodium storage capacity of 375 mAh g-1 at 100 mA g-1 after 200 cycles and provides...
Source: Nano Energy - Category: Nanotechnology Source Type: research
Source: Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy - Category: Endocrinology Tags: Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy Source Type: research
Women whose periods stop before the age of 40 are at greater risk of diabetes, heart disease, strokes, asthma and breast cancer, the study found. The UK menopause average is 51.
Source: the Mail online | Health - Category: Consumer Health News Source Type: news
.
Source: Archives of Physiology and Biochemistry - Category: Physiology Authors: Source Type: research
Isopure Sodium Bicarbonate Mixing and Distribution System (IsoMix PRO) with a Finish Thompson Centrifugal Pump Model #110192-3
Source: Medical Device Recalls - Category: Medical Devices Source Type: alerts
Abstract BackgroundDapagliflozin, a highly selective sodium–glucose cotransporter2 inhibitor, reduces hyperglycemia, body weight, and blood pressure in patients with type 2 diabetes (T2DM). MethodsThis randomized, double‐blind, placebo‐controlled, parallel‐group, 24‐week study (NCT01095666), assessed the efficacy, safety, and tolerability of dapagliflozin as add‐on to metformin in Asian patients with inadequately controlled T2DM (HbA1c 7.5–10.5%). Patients were randomized to receive placebo (n = 145) or dapagliflozin 5 (n = 147) or 10 mg (n = 152). Resu...
Source: Journal of Diabetes - Category: Endocrinology Authors: Tags: Original Article Source Type: research
More News: Diabetes | Dialysis | Endocrinology | Food and Drug Administration (FDA) | Intensive Care | Pyelonephritis | Renal Failure | Sodium | Urinary Tract Infections