Central Sfrp5 regulates hepatic glucose flux and VLDL- triglyceride secretion

Secreted frizzled-related protein 5 (Sfrp5) has been shown to be associated with energy homeostasis and insulin resistance in mouse models of obesity and diabetes. However, its central role in glucose and lipid metabolism is unknown.

Source: Metabolism - Clinical and Experimental - November 22, 2019 Category: Biomedical Science Authors: Yang Li, Mingyuan Tian, Mengliu Yang, Gangyi Yang, Jianrong Chen, Han Wang, Dongfang Liu, Hongyan Wang, Wuquan Deng, Zhiming Zhu, Hongting Zheng, Ling Li Source Type: research