Infection and RNA-seq analysis of a zebrafish tlr2 mutant shows a broad function of this toll-like receptor in transcriptional and metabolic control and defense to Mycobacterium marinum infection

The function of Toll-like receptor 2 (TLR2) in host defense against pathogens, especially Mycobacterium tuberculosis (Mtb) is poorly understood. To investigate the role of TLR2 during mycobacterial infection, we ...

Source: BMC Genomics - November 20, 2019 Category: Genetics & Stem Cells Authors: Wanbin Hu, Shuxin Yang, Yasuhito Shimada, Magnus M ünch, Rubén Marín-Juez, Annemarie H. Meijer and Herman P. Spaink Tags: Research article Source Type: research