Polidocanol versus hypertonic glucose for sclerotherapy treatment of reticular veins of the lower limbs: study protocol for a randomized controlled trial

DiscussionThis project aims to enroll 96 patients and subject them to a double-blind treatment after the randomization process. The design is intended to evaluate efficacy through a primary end point and safety through a secondary end point. Forty-eight patients have currently been enrolled. Preliminary results for these patients showed that 25 received treatment, 2 were excluded, and 22 returned after 7 days and showed no greater adverse events. To date, establishing efficacy criteria has not been possible, and no patients have reached the 60-day return point. These data may help doctors choose the best chemical agent for the treatment of reticular veins.Trial registration: ClinicalTrials.gov Identifier: NCT02054325, 3/02/2014.

Source: Trials - December 19, 2014 Category: Journals (General) Authors: Matheus BertanhaMarcone SobreiraCarlos Pinheiro Lúcio FilhoJamil de Oliveira MariúbaRafael Farres PimentaRodrigo JaldinAndrei MorozRegina MouraHamilton RolloWinston Yoshida Source Type: research