Structure-Assisted Design of Universal Vaccines and Therapeutics Against Influenza Virus

Date: Tuesday, 11 19, 2019; Speaker: Ian A. Wilson, D.Phil., D.Sc., Hanson Professor of Structural Biology , The Scripps Research Institute; Building: Building 10 (Clinical Center); Lipsett Amphitheater; Videocast Event
Source: NIH Calendar of Events - Category: American Health Source Type: events

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Publication date: Available online 6 December 2019Source: American Journal of Kidney DiseasesAuthor(s): Junichi Ishigami, Yingying Sang, Morgan E. Grams, Josef Coresh, Alex Chang, Kunihiro MatsushitaRationale &ObjectiveInfluenza vaccination is recommended for all adults but particularly for older adults and those with high-risk conditions. Reduced kidney function is an important high-risk condition, but the effectiveness of influenza vaccination across kidney function is uncharacterized. We assessed the effectiveness of influenza vaccination among older adults with and without reduced kidney function.Study DesignObserv...
Source: American Journal of Kidney Diseases - Category: Urology & Nephrology Source Type: research
rečková E Abstract Influenza A viruses (IAVs) cause yearly repeating infections in humans. The current vaccination approach is based on the production of virus-neutralizing antibodies. Virus-neutralizing antibodies, however, are closely strain-specific due to the IAV variability. Therefore, antibodies produced during the previous influenza season do not provide sufficient protection against new infection, and, hence, annual revaccination is needed. The utilization of the influenza conserved stem domain of hemagglutinin (HA), the HA2 gp, led to a new vaccine design based on cross-reactive cellular and ...
Source: Acta Virologica - Category: Infectious Diseases Authors: Tags: Acta Virol Source Type: research
Authors: Laguna-Torres VA, Gómez J, Hernández H, Francia-Romero J, Bisso-Andrade A, Guerreros A, Cerna-Barco J, Sanchez-Vergaray E, Gotuzzo E Abstract The importance of surveilling the circulation of the influenza virus and timely vaccination of different populations in Peru was analyzed in three sessions by a group of clinical experts from different specialties. The Peruvian national influenza surveillance system has many selected establishments that have become currently ineffective in terms of a timely report. Most of the samples come from Lima. The viral distribution is inadequately analyzed. The ...
Source: Revista Peruana de Medicina de Experimental y Salud Publica - Category: International Medicine & Public Health Tags: Rev Peru Med Exp Salud Publica Source Type: research
In conclusion, this study suggests promoting initiatives for reducing absenteeism, identifying those factors that would facilitate it, and having a contingency plan prepared in the event of an influenza pandemic. PMID: 31800943 [PubMed - in process]
Source: Revista Peruana de Medicina de Experimental y Salud Publica - Category: International Medicine & Public Health Tags: Rev Peru Med Exp Salud Publica Source Type: research
Conditions:   Selenium Supplementation;   Influenza Vaccination Interventions:   Dietary Supplement: Selenium Supplementation;   Biological: Influenza vaccination Sponsors:   Huazhong University of Science and Technology;   The University of Queensland Recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
Conclusion This study is the first to report on the VE against all types of influenza in all age groups using an RIDT. The VE varied with both age and influenza subtype. PMID: 31787695 [PubMed - as supplied by publisher]
Source: Internal Medicine - Category: Internal Medicine Tags: Intern Med Source Type: research
The AmeriSpeak Spotlight on Health survey found that just 44 percent of responding U.S. adults had received the influenza vaccine as of November 11, while 37 percent said they do not plan to get the shot this year.
Source: Health News - UPI.com - Category: Consumer Health News Source Type: news
In patients with rheumatoid arthritis (RA), a high-dose trivalent inactivated influenza vaccine (HD-TIV) is safe and potentially more immunogenic than a standard-dose quadrivalent vaccine (SD-QIV), a randomized controlled, active-comparator trial suggests.Reuters Health Information
Source: Medscape Medical News Headlines - Category: Consumer Health News Tags: Rheumatology News Source Type: news
Source: U.S. House of Representatives, Committee on Energy and Commerce. Published: 12/4/2019. This one-hour, 51-minute Congressional hearing before the Subcommittee on Oversight and Investigations examines the federal government ’s efforts and forecast for the 2019–2020 influenza season and ongoing influenza-related research and innovation. Speakers discuss why the flu vaccine is more effective for some people, how someone’s health status may affect the body’s immune response, and recent efforts at the National Inst itutes of Health (NIH) to study these issues, with the goal of producing a univers...
Source: Disaster Lit: Resource Guide for Disaster Medicine and Public Health - Category: International Medicine & Public Health Source Type: news
Publication date: Available online 2 December 2019Source: Preventive MedicineAuthor(s): Ian Watson, S. Cristina OanceaAbstractDespite 79,400 deaths due to the influenza (flu) virus during the 2017–18 season,
Source: Preventive Medicine - Category: International Medicine & Public Health Source Type: research
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