The health effects of structural racism

In the United States, the health of African-Americans lags behind most other racial minority groups.   Compared to whites, black men and women face higher risks of chronic illness, infection, and injuries.  Taken altogether, the average life span for African Americans is six years less compared to whites.  If we can begin to acknowledge that health outcomes are often […]Find jobs at  Careers by KevinMD.com.  Search thousands of physician, PA, NP, and CRNA jobs now.  Learn more.
Source: Kevin, M.D. - Medical Weblog - Category: General Medicine Authors: Tags: Policy breast cancer Public Health & Source Type: blogs

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Publication date: Available online 9 December 2019Source: Reports of Practical Oncology &RadiotherapyAuthor(s): R. Soumarová, L. RušinováAbstractAdjuvant radiotherapy after breast cancer surgery is an important part of breast cancer treatment improving local control and overall survival. However, a higher risk of cardiac mortality was observed when conventional radiotherapy techniques were used. Cardiac morbidity and mortality after radiation therapy have been studied in many meta-analyses. In those focused on modern radiotherapy techniques, cardiac morbidity and mortality were no longer presented....
Source: Reports of Practical Oncology and Radiotherapy - Category: Cancer & Oncology Source Type: research
CONCLUSION: Vitrification did not affect preantral follicle morphology or mRNA expression of the apoptosis markers FasL and caspase-3. Further studies are required to establish whether vitrification affects the outcomes of in vitro culture and the maturation of preantral follicles. PMID: 31813207 [PubMed]
Source: Clinical and Experimental Reproductive Medicine - Category: Reproduction Medicine Tags: Clin Exp Reprod Med Source Type: research
Authors: Mabonga L, Kappo AP Abstract Small nuclear ribonucleoprotein polypeptide G (SNRPG), often referred to as Smith protein G (SmG), is an indispensable component in the biogenesis of spliceosomal uridyl-rich small nuclear ribonucleoprotein particles (U snRNPs; U1, U2, U4 and U5), which are precursors of both the major and minor spliceosome. SNRPG has attracted significant attention because of its implicated roles in tumorigenesis and tumor development. Suggestive evidence of its varying expression levels has been reported in different types of cancers, which include breast cancer, lung cancer, prostate cancer ...
Source: American Journal of Translational Research - Category: Research Tags: Am J Transl Res Source Type: research
Full-field digital mammography (FFDM) detects breast cancer better than either...Read more on AuntMinnie.comRelated Reading: DBT finds more cancers of all types than FFDM DBT bests FFDM for surveillance after surgery U.K. study underscores mammography's effectiveness DBT again bests FFDM for screening Digital mammo finds more cancer, but boosts biopsy callbacks
Source: AuntMinnie.com Headlines - Category: Radiology Source Type: news
Healthcare insurance companies should value PET imaging and its cost-effective...Read more on AuntMinnie.comRelated Reading: CMS final rule for MPFS could cost radiology $5B CMS gets pushback on PET fee cuts PSMA-PET/CT most effective for recurrent prostate cancer Editorial slams NRC plan to expand radiopharmaceutical users PET tracers help guide breast cancer therapies
Source: AuntMinnie.com Headlines - Category: Radiology Source Type: news
(Medical University of South Carolina) Tumor volume in a preclinical model of triple negative breast cancer (TNBC) was reduced four times more when an experimental polo-like kinase 1 (PLK1) inhibitor was combined with a standard-of-care chemotherapeutic agent than when the agent was used alone. Hollings Cancer Center scientists at the Medical University of South Carolina reported these findings in PLOS ONE.
Source: EurekAlert! - Cancer - Category: Cancer & Oncology Source Type: news
Psychiatric Services, Ahead of Print.
Source: Psychiatric Services - Category: Psychiatry Authors: Source Type: research
Contributors : Kristine K Sahlberg ; Vessela Kristensen ; Xavier TekpliSeries Type : Expression profiling by high throughput sequencingOrganism : Homo sapiensWe use expression data from breast cancer tumors to define immune clusters in breast cancer. Immune clusters have gradual levels of immune infiltration. In the intermediate immune infiltration cluster, we found a worse prognosis which is independent of known clinicopathological features. We also found the immune clusters associated with treatment response. Further we use gene expression data and deconvolution algorithms to dissect the immune contexture of the clusters.
Source: GEO: Gene Expression Omnibus - Category: Genetics & Stem Cells Tags: Expression profiling by high throughput sequencing Homo sapiens Source Type: research
In this report, we describe our studies on the FOXM1 targeting activities of 1,1-diarylethylene mono- and diamine compounds and their methiodide salts in cell-free, cell-based, and in vivo assays. The compounds bind directly to FOXM1 and alter its proteolytic sensitivity, reduce the cellular level of FOXM1 protein, and suppress the proliferation of breast cancer cells. RNA-seq and gene set enrichment analyses indicate that the compounds NB-73 and NB-55 decrease the expression of FOXM1-regulated genes and suppress gene ontology processes known to be under FOXM1 regulation. Several compounds with favorable pharmacokinetic pr...
Source: GEO: Gene Expression Omnibus - Category: Genetics & Stem Cells Tags: Expression profiling by high throughput sequencing Homo sapiens Source Type: research
AbstractAlthough sentinel lymph node biopsy (SLNB) has become a standard of care for management of axilla in breast cancer patients, the technique of SLNB is still not well defined. Unlike radioactive sulfur colloid which requires nuclear medicine facilities, methylene blue dye is readily available. The purpose of this study is to validate the use of methylene blue dye alone for SLNB in early breast cancer patients. 60 patients of early breast cancer were randomized to receive either methylene blue alone (Group A-30 patients) or a combination of both methylene blue and radioactive colloid (Group B-30 patients) for detectio...
Source: Indian Journal of Surgical Oncology - Category: Cancer & Oncology Source Type: research
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