ANDROMEDA-an investigation of factors influencing the adherence of patients with neovascular age-related macular degeneration using the newly developed patient questionnaire LAF-IVT.
CONCLUSION: The symptoms, barriers, burdens and quality of life effects experienced by patients influence the adherence to treatment and thus the outcome. A better understanding of the patient's views and experiences is the basis for long-term optimization of care. PMID: 31720846 [PubMed - as supplied by publisher]
We describe various retinal image datasets that can be used for deep learning purposes. Applications of deep learning for segmentation of optic disk, optic cup, blood vessels as well as detection of lesions are reviewed. Recent deep learning models for classification of diseases such as age-related macular degeneration, glaucoma, and diabetic retinopathy are also discussed. Important critical insights and future research directions are given.
Publication date: Available online 14 December 2019Source: Progress in Retinal and Eye ResearchAuthor(s): Iqbal Ahmad, Pooja Teotia, Helen Erickson, Xiaohuan XiaAbstractDegeneration of specific retinal neurons in diseases like glaucoma, age-related macular degeneration, and retinitis pigmentosa is the leading cause of irreversible blindness. Currently, there is no therapy to modify the disease-associated degenerative changes. With the advancement in our knowledge about the mechanisms that regulate the development of the vertebrate retina, the approach to treat blinding diseases through regenerative medicine appears a near ...
FRIDAY, Dec. 13, 2019 -- Consumption of a Western dietary pattern is associated with an increased likelihood of developing late age-related macular degeneration (AMD), according to a study published online Dec. 6 in the British Journal of...
Conclusions: The present results highlight a short list of potential DUB candidates for retinal disorders, which require further study. PMID: 31819342 [PubMed - in process]
(University at Buffalo) Participants who ate a diet high in red and processed meat, fried food, refined grains and high-fat dairy were three times more likely to develop late-stage age-related macular degeneration.
CONCLUSION: In this post hoc analysis, fixed dosing with an anti-VEGF agent over 52 weeks eliminated disease activity (absence of both leakage and fluid) in most eyes. The effect of anti-VEGF treatment on leakage/fluid status favoured PC versus occult lesions. PMID: 31826853 [PubMed - as supplied by publisher]
Although the choroid contributes to the pathogenesis of age-related macular degeneration (AMD), the role of retinal perfusion is unclear.
To determine longitudinal changes in the ganglion cell-inner plexiform layer (GC-IPL) thickness of the fellow eyes of patients with neovascular age-related macular degeneration (AMD).
Abstract PURPOSE: To evaluate visual and anatomic outcomes following pars plana vitrectomy and intravitreal or subretinal tissue plasminogen activator for submacular hemorrhage in patients with age-related macular degeneration. METHODS: This was a retrospective study on patients with a minimum follow-up of 12 months undertaken at a tertiary referral center. Data collected include demographic details, visual and optical coherence tomography changes, surgical details, and complications. Surgical results were compared with patients who were age and lesion size matched and treated with anti-vascular endoth...