Dr Le Fanu's online health clinic, Friday 19th December 2014

Concerned about aches and pains? Worried about a medical condition? You can email your questions confidentially to Dr Le Fanu at drjames@telegraph.co.uk. Answers will be published in the health section of the Telegraph website every Friday. Today -Vitamin D, tinnitus, antibiotic reactions and an everyday cure for candida in men.
Source: Telegraph Health - Category: Consumer Health News Tags: statins Dr James Health Clinic James Le Fanu Source Type: news

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Conclusion: The monthly administration of IM NE represents a manageable and effective option, in terms of BMD and bone BM improvement, for the long-term treatment of postmenopausal OP women with gastric intolerance to BPs. This trial is registered with ClinicalTrials.gov Identifier: NCT03699150. PMID: 30881452 [PubMed]
Source: International Journal of Endocrinology - Category: Endocrinology Tags: Int J Endocrinol Source Type: research
Publication date: Available online 18 March 2019Source: Journal of BiotechnologyAuthor(s): R. Gustavsson, C.F. Mandenius, S. Löfgren, T. Scheper, P. LindnerAbstractMicrobial contamination in mammalian cell cultures causing rejected batches is costly and highly unwanted. Most methods for detecting a contamination are time-consuming and require extensive off-line sampling. To circumvent these efforts and provide a more convenient alternative, we used an online in situ microscope to estimate the cell diameter of the cellular species in the culture to distinguish mammalian cells from microbial cells depending on their siz...
Source: Journal of Biotechnology - Category: Biotechnology Source Type: research
Publication date: Available online 18 March 2019Source: Redox BiologyAuthor(s): Shen-Fei Wang, Xin Liu, Mo-Yu Ding, Shuangcheng Ma, Jing Zhao, Ying Wang, Shaoping LiAbstractReducing agents are crucial for the management of maladaptive inflammation-induced macrophage death and hematopoietic toxicity of chemotherapy. 2-O-β-d-glucopyranosyl-l-ascorbic acid (AA-2βG), a unique AA (or vitamin C) derivative identified in Lycium barbarum, exhibited enhanced free radical scavenging activity compared with AA and its synthetic derivative AA-2αG. AA-2βG protected hydrogen peroxide-induced cell death in murine macr...
Source: Redox Biology - Category: Biology Source Type: research
ConclusionMale-specific prevention and treatment strategies for ASCVD are needed in eastern China. In addition, WHR, WHtR, non-HDL-C, and TC/HDL-C which not included in the the China-PAR equation were also independently associated with 10-year ASCVD risk score categories.
Source: Biomedical and Environmental Sciences - Category: Biomedical Science Source Type: research
In this study, we sought to determine the pharmacological effects of JKW, and the mechanisms responsible, on hepatic steatosis in free fatty acids (FFAs)-stimulated HepG2 cells and in high-fat diet (HFD)-fed obese mice. Treatment with JKW significantly decreased intracellular lipid accumulation in vitro. Furthermore, JKW significantly triggered the phosphorylation of insulin receptor substrate-1 (IRS-1) and phosphoinositide 3-kinase (PI3K) and modulated glucose and lipid metabolism via an AMP-activated protein kinase (AMPK) signaling pathway. Analysis of serum parameters in HFD-fed mice showed that JKW improved glucose lev...
Source: Evidence-based Complementary and Alternative Medicine - Category: Complementary Medicine Tags: Evid Based Complement Alternat Med Source Type: research
New J. Chem., 2019, Advance Article DOI: 10.1039/C8NJ06168H, PaperXiwen Yang, Shaonan Chen, Hang Luo, Haoran Xu, Sheng Chen Liquid crystal polymers with cholesterol side-chains formed different smectic A phases under the influence of the main-chain structure and flexible spacer length. To cite this article before page numbers are assigned, use the DOI form of citation above. The content of this RSS Feed (c) The Royal Society of Chemistry
Source: RSC - New J. Chem. latest articles - Category: Chemistry Authors: Source Type: research
CrystEngComm, 2019, Accepted Manuscript DOI: 10.1039/C9CE00013E, PaperAnna Zep, Kamila Pruszkowska, Lukasz Dobrzycki, Katarzyna Sektas, Piotr Sza łański, Paulina Halina Marek, Michal Ksawery Cyranski, Rafal Ryszard Sicinski Homologue series of cholesterol based liquid crystalline bent-shaped dimers with different length of a terminal alkoxy chain have been synthesized, and characterized by polarizing optical microscopy, differential scanning calorimetry, powder... The content of this RSS Feed (c) The Royal Society of Chemistry
Source: RSC - CrystEngComm latest articles - Category: Chemistry Authors: Source Type: research
This article is licensed under aCreative Commons Attribution-NonCommercial 3.0 Unported Licence.Taiki Miyazawa, Akira Matsumoto, Yuji Miyahara A redox-sensitive inter-conversion between ascorbic acid (ASC) and its oxidized form dehydroascorbic acid (DHA) in intracellular environment has been of exceptional interest to recent metabolomics and pharmaceutical research. We developed... The content of this RSS Feed (c) The Royal Society of Chemistry
Source: RSC - Analyst latest articles - Category: Chemistry Authors: Source Type: research
Publication date: Available online 18 March 2019Source: Environmental Toxicology and PharmacologyAuthor(s): Mohamed M. Abdel-Daim, Ismail A.M. Eissa, Ahmed Abdeen, Hany M.R. Abdel-Latif, Mona Ismail, Mahmoud A.O. Dawood, Ahmed M. HassanAbstractIndustrial products contained nano-zinc oxide (ZnONP) can gain access to the aquaculture environment causing hazardous effects on the living biota. Therefore, this work was planned to examine the ameliorative effects of dietary supplementation of lycopene (LYC), resveratrol (RES) against ZnONP toxicity in Nile tilapia. Five groups with 20 fish each were used; Control, received tap wa...
Source: Environmental Toxicology and Pharmacology - Category: Environmental Health Source Type: research
ConclusionThe extracted rules after experimentation are understandable and informative to the technical and nontechnical community to predict HBP.
Source: Clinical Epidemiology and Global Health - Category: Epidemiology Source Type: research
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