Methamphetamine Induces Intestinal Inflammatory Injury via Nod-Like Receptor 3 Protein (NLRP3) Inflammasome Overexpression In Vitro and In Vivo.
CONCLUSIONS METH, in addition to being a confirmed neurotoxic drug, can also cause severe intestinal inflammatory injury via NLRP3 inflammasome overexpression. NF-kappaB may be an activator of the NLRP3 inflammasome in METH intestinal inflammatory injury.
PMID: 31712546 [PubMed - in process]
Source: Methods of Information in Medicine - Category: Information Technology Authors: Zhao J, Shen S, Dai Y, Chen F, Wang K Tags: Med Sci Monit Source Type: research