Chemical design and bioefficacy screening of new insect growth regulators as potential insecticidal agents against Spodoptera littoralis (Boisd.)

Publication date: Available online 12 November 2019Source: Biotechnology ReportsAuthor(s): Antar A. Abdelhamid, M.M. Elwassimy, Safwat A. Aref, Mohamed A. GadAbstractThe 13 new compounds were chemically synthesized and their spectroscopic analysis was done to determine their chemical structure. All the compounds were screened for their insecticidal potential against Spodoptera littoralis (Boisd.). Among the tested compounds, the compound 13 was found to be the most potent. It displayed one fold more activity than a reported insect growth regulator, fenoxycarb. The other target compounds demonstrated weak to strong toxicological activities against Spodoptera littoralis (Boisd.).Graphical abstractHighlights•The present work aimed to find new growth inhibitory agents against Spodoptera littoralis (Boisd.).•New derivatives of 4-aminophenol (as insect growth regulators) were synthesized in the laboratory•The chemically structure of every one of target compounds was elucidated by spectroscopic techniques.•The insecticidal activity of the synthesized compounds was evaluated against Spodopetera littoralis (Boisd.).•The activity was compared with control compound Fenoxycarb.
Source: Biotechnology Reports - Category: Biotechnology Source Type: research