More Data Will Inform Place of SGLT2 Inhibitors in DiabetesMore Data Will Inform Place of SGLT2 Inhibitors in Diabetes
A comparison of canagliflozin with glimepiride as an add-on to metformin in type 2 diabetes adds some knowledge to help guide use of the new SGLT2 inhibitors. But more will be needed, says an editorial. Medscape Medical News
In conclusion, the protective effect of HDL to counter ER stress and β-cell death involves the transport, generation, and mobilization of oxysterols for activation of the Hh signaling receptor SMO
This article aims for summarizing current clinical knowledge on screening, diagnosis, and treatment and gives an overview on the pathophysiology of exocrine pancreatic insufficiency in diabetes.Recent FindingsRecent studies reveal novel insights into the close interaction of acinar, ductal, and endocrine cells and the gut-pancreas axis.SummaryExocrine pancreatic insufficiency is a clinically relevant, frequent but poorly understood disorder in both type 1 and type 2 diabetes.
Publication date: Available online 31 March 2020Source: Diabetes &Metabolic Syndrome: Clinical Research &ReviewsAuthor(s): Andrea Da Porto, Viviana Casarsa, Gianluca Colussi, Cristiana Catena, Alessandro Cavarape, Leonardo Sechi
ABSTRACTSerum lipid abnormalities (dyslipidemias) are major risk factors for cardiovascular disease in type 2 diabetes. The features of diabetic dyslipidemia are elevated plasma concentrations of triglyceride (TG) ‐rich lipoproteins (TRLs), small dense low‐density lipoprotein cholesterol (sdLDL‐C) and decreased plasma high‐density lipoprotein cholesterol (HDL‐C) concentration
ConclusionsOur results indicated a higher risk of diabetes among never ‐smoking Japanese women with higher exposure to passive smoking from a spouse.
TYPE 2 diabetes is an extremely common and serious problem faced by many worldwide. The condition affects insulin in the body, and this affects the pancreas. Thankfully, adding this delicious spice to your meals could greatly help to lower blood sugar and keep you healthy.
Diabetes Core Update is a monthly podcast that presents and discusses the latest clinically relevant articles from the American Diabetes Association’s four science and medical journals – Diabetes, Diabetes Care, Clinical Diabetes, and Diabetes Spectrum. Each episode is approximately 20 minutes long and presents 5-6 recently published articles from ADA journals. Intended for practicing physicians and health care professionals, Diabetes Core Update discusses how the latest research and information published in journals of the American Diabetes Association are relevant to clinical practice and can be applied in a ...
TUESDAY, March 31, 2020 -- Artificial intelligence (AI) may be able to identify people who will develop type 2 diabetes, researchers say. For the study, the researchers used machine learning AI to analyze more than 509,000 annual health checkup...
Publication date: Available online 29 March 2020Source: Microbes and InfectionAuthor(s): Mohammad Abdul Alim, Andreas Kupz, Suchandan Sikder, Catherine Rush, Brenda Govan, Natkunam Ketheesan
AbstractAims/IntroductionWhile moderate alcohol consumption lowers the risk of type 2 diabetes in European populations, the same cannot be assumed for Japanese patients with diabetes related to low insulin secretion rather than resistance. We aimed to evaluate the effects of daily alcohol consumption on glucose tolerance and diabetes development risk in Japanese populations.Materials and MethodsThis retrospective study randomly enrolled 452 men and 659 women aged 40 –78 years in 2005 (Gifu, Japan). The participants completed a 75‐g oral glucose tolerance test and medical questionnaire. The homeostasis model assessm...