M300 food allergy to fungal diamonds

Known as the “diamond of the kitchen”, truffles are the fruiting body of the fungi genus Tuber. In an effort to duplicate this desired flavor, truffle flavoring is made by combining olive oil and the synthetic 2,4-dithiapentane (DTP).
Source: Annals of Allergy, Asthma and Immunology - Category: Allergy & Immunology Authors: Tags: Food Allergy Source Type: research

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We examined our primary care birth cohort of 158,510 pediatric patients, of whom 214 patients met 2017 FPIES diagnostic criteria. We measured the influence of FPIES on developing subsequent atopic disease.ResultsPediatric FPIES incidence was between 0.17% and 0.42% depending on birth year. As in prior reports, most patients had an acute presentation (78%), and milk, soy, oat, rice, potato, and egg were common triggers. The mean age of diagnosis was 6.8 months. Atopic comorbidity was higher in patients with FPIES compared with healthy children (AD, 20.6% vs 11.7%; IgE-FA, 23.8% vs 4.0%; asthma, 26.6% vs 18.4%; AR, 28.0% vs 16.7%; P
Source: The Journal of Allergy and Clinical Immunology: In Practice - Category: Allergy & Immunology Source Type: research
AbstractPurpose of ReviewInvestigational allergen immunotherapies (AITs) including oral immunotherapy (OIT), sublingual immunotherapy (SLIT), and epicutaneous immunotherapy (EPIT) have proven to increase allergen thresholds required to elicit an allergic reaction in a majority of subjects. However, these studies lack consistent biomarkers to predict therapy outcomes. Here, we will review biomarkers that are currently being investigated for AIT.Recent FindingsThe mechanisms underlying the therapeutic benefit of AIT involve various cell types, including mast cells, basophils, T cells, and B cells. Skin prick and basophil act...
Source: Current Allergy and Asthma Reports - Category: Allergy & Immunology Source Type: research
Peanut allergy affects 1-2% of individuals in the United States, and is increasing in prevalence.1-4 Although there is accumulating data on immunotherapy for peanut allergy,5-8 the cornerstone of management remains strict avoidance of peanut protein, maintenance of an emergency action plan and prompt use of epinephrine to treat systemic reactions in case of an accidental exposure, which occurs in up to 12-15% of peanut-allergic individuals annually.9,10 Peanut allergy significantly impacts quality of life,11 as it is typically lifelong, is the leading cause of food-induced anaphylaxis in children, and the leading cause of ...
Source: Annals of Allergy, Asthma and Immunology - Category: Allergy & Immunology Authors: Source Type: research
AbstractPurpose of ReviewThe purpose of this review article is to discuss the recent literature around methods of prevention of food allergies other than peanut allergy.Recent FindingsWhile the most robust data to date exists for peanut, there are emerging studies suggesting a beneficial effect to early introduction of cooked egg, and cow ’s milk as well. While the literature is sparse for other allergens such as tree nuts, finned fish, and shellfish, the mechanism of sensitization is thought to be the same and no study to date has demonstrated a harm with allergenic introduction in the 4–6 months of age window...
Source: Current Allergy and Asthma Reports - Category: Allergy & Immunology Source Type: research
This study examined whether infants aged 0 –3 months exhibited long-term effects of using a moisturizer skincare intervention and whether a short-term skin problem resulted in the subsequent development of food...
Source: Allergy, Asthma and Clinical Immunology - Category: Allergy & Immunology Authors: Tags: Research Source Type: research
Immune dysfunction and abnormal immune response may be associated with certain mechanisms underlying autism spectrum disorder (ASD). The early evidence for this link was based on the increased incidence of ASD in children with a history of maternal infection during pregnancy. Observational studies show increased prevalence of immune-related disorders—ranging from atopy, food allergy, viral infections, asthma, primary immunodeficiency, to autoimmune disorders—in individuals with ASD and their families. Evidence of neuroglial activation and focal brain inflammation in individuals with ASD implies that the central...
Source: Frontiers in Psychiatry - Category: Psychiatry Source Type: research
AbstractPurpose of ReviewOver the last decade, there has been a spark in innovation in the development of therapies for food allergy. Herein, we describe the background and recent advances for food-specific immunotherapies including epicutaneous (EPIT), sublingual (SLIT), and subcutaneous (SCIT).Recent FindingsStudies have progressed most quickly for the treatment of peanut allergy. Data from the phase 3 EPIT trial add to the accumulating evidence that this will be a viable therapy for peanut allergy. Studies for SLIT and SCIT remain in earlier phases with promising results.SummaryThis is an exciting era for the treatment ...
Source: Current Allergy and Asthma Reports - Category: Allergy & Immunology Source Type: research
Allergic diseases such as atopic dermatitis (AD), food allergy (FA), asthma and allergic rhinitis (AR) are common; according to a national birth cohort study in Japan, almost half of pregnant women reported a history of allergic disease.1 Given that genetic factors, including family history, are predictors of allergic diseases in offspring, we expect the birth of many infants who carry a high risk of developing allergies. Among allergy prevention strategies, the effectiveness of primary prevention of eczema in high-risk infants by the topical application of emollient during the neonatal period has been demonstrated in two ...
Source: Annals of Allergy, Asthma and Immunology - Category: Allergy & Immunology Authors: Tags: Letters Source Type: research
We examined our primary care birth cohort of 158,510 pediatric patients, of which 214 patients met 2017 FPIES diagnostic criteria. We measured the influence of FPIES on developing subsequent atopic disease.ResultsPediatric FPIES incidence was between 0.17% and 0.42% depending on birth year. As in prior reports, most patients had an acute presentation (78%) and milk, soy, oat, rice, potato, and egg were common triggers. The mean age of diagnosis was 6.8 months. Atopic comorbidity was higher in FPIES patients compared to healthy children (AD, 20.6% vs. 11.7%; IgE-FA, 23.8% vs. 4.0%; asthma, 26.6% vs. 18.4%; AR, 28.0% vs. 16.7%; p
Source: The Journal of Allergy and Clinical Immunology: In Practice - Category: Allergy & Immunology Source Type: research
Conclusions: Thus, food allergy precedes and predisposes to asthma. The food allergy in asthma characterized by predominance of sensitization to ovalbumin and cow milk and its components.
Source: European Respiratory Journal - Category: Respiratory Medicine Authors: Tags: Allergy and immunology Source Type: research
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