Faecalibacterium prausnitzii and human intestinal health.

Faecalibacterium prausnitzii and human intestinal health.
Curr Opin Microbiol. 2013 Jul 3;
Authors: Miquel S, Martín R, Rossi O, Bermúdez-Humarán L, Chatel J, Sokol H, Thomas M, Wells J, Langella P
Abstract
Faecalibacterium prausnitzii is the most abundant bacterium in the human intestinal microbiota of healthy adults, representing more than 5% of the total bacterial population. Over the past five years, an increasing number of studies have clearly described the importance of this highly metabolically active commensal bacterium as a component of the healthy human microbiota. Changes in the abundance of F. prausnitzii have been linked to dysbiosis in several human disorders. Administration of F. prausnitzii strain A2-165 and its culture supernatant have been shown to protect against 2,4,6-trinitrobenzenesulfonic acid (TNBS)-induced colitis in mice. Here, we discuss the role of F. prausnitzii in balancing immunity in the intestine and the mechanisms involved.
PMID: 23831042 [PubMed - as supplied by publisher]

Source: Current Opinion in Microbiology - July 3, 2013 Category: Microbiology Authors: Miquel S, Martín R, Rossi O, Bermúdez-Humarán L, Chatel J, Sokol H, Thomas M, Wells J, Langella P Tags: Curr Opin Microbiol Source Type: research