Stomach-churning footage shows large parasites wriggling around in man's liver

The worm-like creatures, known as liver flukes, infected the 40-year-old after he ate raw watercress on a farm in Mexico. One was filmed using its suckers to cling to the walls of his organ.
Source: the Mail online | Health - Category: Consumer Health News Source Type: news

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Abstract Sri Lanka reports a large epidemic of cutaneous leishmaniasis (CL) caused by an atypical L. donovani while regional leishmaniasis elimination drive aims at achieving its targets in 2020. Visceralization, mucotrophism, and CL associated poor treatment response were recently reported. Long-term clinico-epidemiological trends (2001-2013) in this focus were examined for the first time. Both constant and changing features were observed. Sociodemographic patient characteristics that differ significantly from those of country profile, microchanges within CL profile, spatial expansion, constant biannual seasonal ...
Source: Biomed Res - Category: Research Authors: Tags: Biomed Res Int Source Type: research
Publication date: Available online 13 November 2019Source: Saudi Pharmaceutical JournalAuthor(s): María Esperanza Adrover, Marisa Pedernera, Magali Bonne, Bénédicte Lebeau, Verónica Bucalá, Loreana GalloAbstractAlbendazole (ABZ, anti-parasitic active pharmaceutical ingredient) is a crystalline low water-soluble drug, thus the dissolution rate in gastrointestinal fluids is limited. Consequently, the improvement of the water solubility and dissolution rate of ABZ implies a great challenge for a more efficient treatment of hydatidosis. In this context, SBA-15 and SBA-16 ordered mesoporous si...
Source: Saudi Pharmaceutical Journal - Category: Drugs & Pharmacology Source Type: research
Publication date: April 2020Source: Parasitology International, Volume 75Author(s): Hideyuki Iriko, Tomoko Ishino, Mayumi Tachibana, Ayaka Omoda, Motomi Torii, Takafumi TsuboiAbstractPlasmodium falciparum proteins involved in vascular endothelial cell adherence are transported to the surface of infected erythrocytes. These proteins are exported through parasite-derived membrane structures within the erythrocyte cytoplasm called Maurer's clefts. Skeleton binding protein 1 (SBP1) is localized in the Maurer's clefts and plays an important role in transporting molecules to the surface of infected erythrocytes. Details of the t...
Source: Parasitology International - Category: Parasitology Source Type: research
Publication date: Available online 12 November 2019Source: Veterinary ParasitologyAuthor(s): Pornanan Kueakhai, Kulathida Chaithirayanon, Athit Chaiwichien, Tepparit Samrit, Supawadee Osotprasit, Phawiya Suksomboon, Wipaphorn Jaikua, Prasert Sobhon, Narin ChangklungmoaAbstractGlutathione peroxidases (GPx), major antioxidant enzymes, secreted by Fasciola spp., are important for the parasite evasion and protection against the host’s immune responses. In the present study, a monoclonal antibody (MoAb) against recombinant F. gigantica glutathione peroxidase (rFgGPx) was produced by hybridoma technique using spleen cells ...
Source: Veterinary Parasitology - Category: Veterinary Research Source Type: research
Publication date: Available online 12 November 2019Source: MicronAuthor(s): Andrezza Raposo Borges de Melo, Taciana Mirely Maciel Higino, Aline Dulce Pitt da Rocha Oliveira, Adriana Fontes, Diego César Nunes da Silva, Maria Carolina Accioly Brelaz de Castro, José Arimatéia Dantas Lopes, Regina Celia Bressan Queiroz de FigueiredoAbstractChagas disease, caused by the protozoan Trypanosoma cruzi, is considered a public health problem. The current chemotherapy for this illness causes serious side effects and its use in the chronic phase of the disease is still controversial. In this sense, the investigatio...
Source: Micron - Category: Biology Source Type: research
Publication date: Available online 13 November 2019Source: Journal of Theoretical BiologyAuthor(s): Robert J. Hardwick, Carolin Vegvari, James E. Truscott, Roy M. AndersonAbstractBuilding on past research, we here develop an analytic framework for describing the dynamics of the transmission of soil-transmitted helminth (STH) parasitic infections near the transmission breakpoint and equilibria of endemic infection and disease extinction, while allowing for perturbations in the infectious reservoir of the parasite within a defined location. This perturbation provides a model for the effect of infected human movement between ...
Source: Journal of Theoretical Biology - Category: Biology Source Type: research
AbstractChagas disease or American trypanosomiasis is a major public health problem in Latin America. Approximately seven million people are currently infected worldwide. Despite the efforts to develop new drugs, only two nitroheterocyclic drugs (nifurtimox and benznidazole) are available for the treatment of Chagas disease, These drugs have been available since the 1970s, and no new drugs have been approved. Due to the lack of alternatives for the treatment of this disease, this review describes recent advances (2013 –2019) concerning nitroheterocyclic compounds with activity againstT. cruzi parasites, as well as ne...
Source: Medicinal Chemistry Research - Category: Chemistry Source Type: research
The objective of the present st...
Source: Journal of Medicinal Plants Research - Category: Complementary Medicine Source Type: research
In conclusion, increased levels of f-CP are shown as a marker of an inflammatory disease of the lower gastrointestinal tract in infected humans. There is continues controversy about the pathogenicity of D. fragilis in symptomatic and asymptomatic patients. The findings of this study contribute to the ongoing debate about the pathogenicity of D. fragilis. In our study, the potential pathogenicity of D. fragilis is associated with increased f-CP concentrations with parasite detection in the fecal samples and therefore we assume that the parasite is not only a harmless commensal. In summary, higher levels of f-CP found in D. ...
Source: Microbial Pathogenesis - Category: Infectious Diseases Source Type: research
Toxoplasma gondii engenders the common parasitic disease toxoplasmosis in almost all warm-blooded animals. Being a critical secretory protein, ROP18 is a major virulence factor of Toxoplasma. There are no reports about ROP18 detection in human serum samples with different clinical manifestations. New aptamers against ROP18 protein were developed through Systematic Evolution of Ligands by Exponential enrichment (SELEX). An Enzyme-Linked Aptamer Assay (ELAA) platform was developed using SELEX-derived aptamers, namely AP001 and AP002. The ELAA was used to evaluate total antigen from T. gondii RH strain (RH Ag) and recombinant...
Source: Frontiers in cellular and infection microbiology - Category: Microbiology Source Type: research
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