Genetic variability in Iranian limb ‐girdle muscular dystrophy type 2B patients: An evidence of a founder effect

ConclusionTwo of the other six families are from the same ethnicity and share the same mutation and haplotype patterns, suggesting a founder mutation. Genetic analysis of dysferlinopathy can prevent a wrong diagnosis of myositis for these patients.

Source: Molecular Genetics & Genomic Medicine - November 5, 2019 Category: Genetics & Stem Cells Authors: Marzieh Mojbafan, Shirzadeh Tina, Fatemeh Zafarghandi Motlagh, Andrei Surguchov, Yalda Nilipour, Sirous Zeinali Tags: ORIGINAL ARTICLE Source Type: research