Gender Differences in Pre- and Postoperative Health-Related Quality of Life Measures in Patients Who Have Had Decompression Surgery for Lumbar Spinal Stenosis.

This study aimed to investigate the gender difference in pre- and postoperative health-related quality of life (HRQOL) in patients who have had decompression surgery for lumbar spinal stenosis (LSS). Overview of Literature: Gender differences may contribute to variations in disease presentations and health outcomes. The influence of gender on pre- and postoperative HRQOL in spinal disorders remains unclear. Methods: We reviewed 125 patients (79 men and 46 women) who had lumbar spinous process splitting laminectomy (LSPSL) for LSS. We assessed the following clinical information: Japanese Orthopedic Association (JOA) score; numerical rating scale (NRS) for low back pain (LBP), leg pain, and leg numbness; Zurich Claudication Questionnaire; JOA Back Pain Evaluation Questionnaire; Roland- Morris Disability Questionnaire (RMDQ); and Short Form 8 (SF-8) as HRQOL. We compared the HRQOLs of men and women pre- and postoperatively. Results: Although the preoperative NRS results for LBP were significantly higher in women (p
Source: Asian Spine Journal - Category: Orthopaedics Tags: Asian Spine J Source Type: research

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Authors: Li S, Ou Y, Li C, Wei W, Lei L, Zhang Q Abstract Acute spinal cord injury (SCI) has a high rate of disability and mortality. Although secondary SCI results in local tissue hypoxia and the release of inflammatory mediators, it is both controllable and reversible. Therefore, timely rehabilitation treatment is beneficial for the partial recovery of patients with SCI. The present study aimed to investigate the use of methylprednisolone combined with high-frequency electrotherapy as a method of rehabilitation treatment in rats with SCI. The rat SCI model was prepared using the modified Allen's method with the a...
Source: Experimental and Therapeutic Medicine - Category: General Medicine Tags: Exp Ther Med Source Type: research
Authors: Chu Y, Ge W, Wang X Abstract MicroRNAs (miRNAs) play crucial roles in the pathogenesis of neuropathic pain. The present study investigated the effects of miR-448 on the progression of neuropathic pain in a rat model of chronic constriction injury (CCI) of the sciatic nerve. Reverse-transcription quantitative polymerase chain reaction was conducted to detect the gene expression. The paw withdrawal threshold (PWT) and paw withdrawal latency (PWL) were used to assess the pain threshold. The protein expression levels of interleukin (IL)-6, IL-1β and tumor necrosis factor-α (TNF-α) were detecte...
Source: Experimental and Therapeutic Medicine - Category: General Medicine Tags: Exp Ther Med Source Type: research
Discussion: The wheelchair particularities that we pursue, and which are distinguished from the other models, is the fact that the wheelchair is powered, pliable and allows verticalization, hopefully at a price comparable or even lower than the current state of the art models (but none of them succeeded by now to fulfil all this three basic functions on a single "all in one" such device). Hence, if our optimized prototype will achieve technical and clinical validation, this will result in a significant enhancement of autonomy and QoL for the users. PMID: 31803294 [PubMed]
Source: Journal of Medicine and Life - Category: General Medicine Tags: J Med Life Source Type: research
Publication date: 1 January 2020Source: Colloids and Surfaces B: Biointerfaces, Volume 185Author(s): Furqan A. Maulvi, Lakshmi V. Pillai, Kajal P. Patel, Ankita R. Desai, Manish R. Shukla, Ditixa T. Desai, Hetal P. Patel, Ketan M. Ranch, Shailesh A. Shah, Dinesh O. ShahAbstractLidocaine is widely used as a local anaesthetic in the clinical practice to manage pre- and post-operative pain, skin burns, etc. However, the short duration of action (
Source: Colloids and Surfaces B: Biointerfaces - Category: Biochemistry Source Type: research
Fight Aging! publishes news and commentary relevant to the goal of ending all age-related disease, to be achieved by bringing the mechanisms of aging under the control of modern medicine. This weekly newsletter is sent to thousands of interested subscribers. To subscribe or unsubscribe from the newsletter, please visit: https://www.fightaging.org/newsletter/ Longevity Industry Consulting Services Reason, the founder of Fight Aging! and Repair Biotechnologies, offers strategic consulting services to investors, entrepreneurs, and others interested in the longevity industry and its complexities. To find out m...
Source: Fight Aging! - Category: Research Authors: Tags: Newsletters Source Type: blogs
All people are the same; only their habits differ. ~ Confucius This is a post about what keeps us stuck and sets us free, about the good news behind bad luck, and the wrong way to want the right thing: It’s about our habits. Human beings are creatures of habit — even emotionally. But why is this? Why do we fall into routines? And why is it so hard to break a habit? The short answer is something called set point. You’re probably familiar with this idea if you have ever been on a diet or had a new year’s resolution. They both start well. You are going to make a change in your life and you are ready fo...
Source: World of Psychology - Category: Psychiatry & Psychology Authors: Tags: Habits Happiness Proof Positive Self-Help Appreciation Gratitude habituation Source Type: blogs
Abstract OBJECTIVEPatients with lumbar spinal stenosis (LSS) tend to bend forward to relieve neurological symptoms. They therefore have a positive sagittal vertical axis (SVA). The importance of the SVA value is well known in the field of adult spinal deformity; however, little is known about its impact on LSS. The authors sought to investigate the impact of sagittal spinopelvic alignment on clinical outcome and health-related quality of life (HRQOL) after decompression surgery for LSS.METHODSThe authors retrospectively reviewed 83 patients who underwent lumbar decompression without fusion between January 2014 and...
Source: Journal of Neurosurgery.Spine - Category: Neurosurgery Authors: Tags: J Neurosurg Spine Source Type: research
ConclusionsIncreasing severity of SedSign indicates progressively smaller dural sac CSA, but there is an inconsistent association with clinical symptoms. Therefore, it is reasonable to suggest that spinal stenosis is severe in patients with severe symptoms.
Source: European Spine Journal - Category: Orthopaedics Source Type: research
Authors: Kim K, Shin KM, Lee JH, Seo BN, Jung SY, Youn Y, Lee SH, Kim J, Qu W, Kim TH Abstract This is a study protocol for a pilot three-armed randomized controlled trial on nonsurgical integrative Korean medicinal treatment for symptomatic lumbar spinal stenosis (LSS). Thirty-six participants who have been diagnosed with (LSS) and recommended for spinal surgery by neurosurgeons or orthopedics and have had spinal symptoms such as severe low back pain and neurological claudication regardless of at least three months of conservative treatments will be recruited. Participants will be randomly assigned to be one of th...
Source: Evidence-based Complementary and Alternative Medicine - Category: Complementary Medicine Tags: Evid Based Complement Alternat Med Source Type: research
Conclusion: This trial failed to demonstrate a benefit of OH or PA in patients experiencing neurogenic claudication. Considering the potential negative side effects of chronic opioid use, additional research is necessary to evaluate the efficacy of sustained opioid treatment specifically for neurogenic claudication. Level of Evidence: 2
Source: Spine - Category: Orthopaedics Tags: Randomized Trial Source Type: research
More News: Back Pain | Disability | Intermittent Claudication | Japan Health | Laminectomy | Low Back Pain | Lumbar Spinal Stenosis | Men | Orthopaedics | Pain | Study | Women