Tear and serum interleukin-8 and serum CX3CL1, CCL2 and CCL5 in sulfur mustard eye-exposed patients.

CONCLUSION: The higher level of CX3CL1 and consistent levels of IL-8/CXCL8, MCP-1/CCL2, and RANTES/CCL5 in SM-exposed individuals may indicate an anti-inflammatory response against the destructive effects of SM gas. High tear level of IL-8/CXCL8 reflects the severity of ocular surface abnormalities, yet significantly low tear level found in mild SM-exposed subgroup compared with the control group. The lower levels of CX3CL1 and RANTES/CCL5 may represent the different pathophysiology which requires further studies.
PMID: 31669888 [PubMed - as supplied by publisher]

Source: International Immunopharmacology - October 23, 2019 Category: Allergy & Immunology Authors: Ghazanfari T, Ghasemi H, Yaraee R, Mahmoudi M, Javadi MA, Soroush MR, Faghihzadeh S, Majd AMM, Shakeri R, Babaei M, Heidary F, Hassan ZM Tags: Int Immunopharmacol Source Type: research