Long-term follow-up of antibody titers against measles, mumps, and rubella in recipients of allogenic hematopoietic cell transplantations

Infections are a major cause of morbidity and mortality in recipients of allogeneic hematopoietic cell transplantations (HCT) [1,2]. Whether or not immune protection can be transferred from donor to host by adoptive transplantation of mature lymphocytes within an allograft has not been completely clarified [2 –7]. Likewise, little is known about the persistence of residual host-type memory B and plasma cells, their ability to provide protective antibodies post allogeneic HCT, and whether this host-type immunity is influenced by clinical parameters, such as transplant conditioning and pharmacological im munosuppression.
Source: Biology of Blood and Marrow Transplantation - Category: Hematology Authors: Source Type: research