Clinical Effects of Mindfulness-Based Intervention in Patients With First Episode Psychosis and in Individuals With Ultra-High Risk for Transition to Psychosis: A Review

Conclusion: Future sham-controlled studies with large sample sizes are needed to definitively conclude on the clinical interest of mindfulness-based interventions in FEP patients and UHR individuals as well as to understand their underlying mechanisms of action.
Source: Frontiers in Psychiatry - Category: Psychiatry Source Type: research

Related Links:

Publication date: Available online 7 December 2019Source: Saudi Pharmaceutical JournalAuthor(s): Kinga OstrowskaAbstractA number of psychiatric disorders, including anxiety, schizophrenia, Parkinson’s disease, depression and others CNS diseases are known to induce defects in the function of neural pathways sustained by the neurotransmitters, like dopamine and serotonin. N-arylpiperazine moiety is important for CNS-activity, particularly for serotonergic and dopaminergic activity. In the scientific literature there are many examples of coumarin-piperazine derivatives, particularly with arylpiperazines linked to a coum...
Source: Saudi Pharmaceutical Journal - Category: Drugs & Pharmacology Source Type: research
ConclusionsRumination is known to be associated with poor prognosis in mental health. This study suggests that rumination is a maladaptive coping style associated not only with worry, distress and illness severity, but also with socioeconomic status. Also, rumination demonstrated a specific association with panic disorder.
Source: Journal of Psychiatric Research - Category: Psychiatry Source Type: research
AbstractMajor psychiatric traits are genetically inter-correlated with one another, but it not well known which genes play pleiotropic effects across different traits. We curated and compared genes identified from large-scale genome-wide association studies for seven psychiatric traits, including depression, bipolar disorder, schizophrenia, autism spectrum disorder, attention-deficit/hyperactivity disorder, anxiety and neuroticism. We then explored biological functions of the top pleiotropic genes. A total of 243 cross-trait genes were identified for the seven traits. Except for autism spectrum disorder, there was signific...
Source: Human Genetics - Category: Genetics & Stem Cells Source Type: research
Scientists from 22 institutions, including UCLA, are recommending early diagnosis, prevention and treatment of severe chronic inflammation to reduce the risk of chronic disease and death worldwide.The group of international experts, which also includes scientists from the National Institutes of Health, Stanford University, Harvard Medical School, Columbia University Medical Center and University College London, point to inflammation-related diseases as the cause of 50 percent of all deaths worldwide.Inflammation is a naturally occurring response by the body ’s immune system that helps fight illness and infection. Whe...
Source: UCLA Newsroom: Health Sciences - Category: Universities & Medical Training Source Type: news
Am I an Alcoholic? Alcoholism (also known as Alcohol Use Disorder, or AUD) is a chronic, relapsing disease affecting millions of individuals in the United States. According to the 2017 National Survey on Drug Use and Health (NSDUH), 51 percent of the population aged 12 and older reported binge drinking in the past month. More than 14 million individuals aged 12 and older were suffering from alcoholism. And each year, more than 2,200 individuals die due to alcohol poisoning. Many may come to wonder, “Am I an alcoholic?” What Causes Alcoholism? Some individuals are more prone to alcoholism than others. Alcoholism...
Source: Cliffside Malibu - Category: Addiction Authors: Tags: Alcohol Alcoholism alcohol abuse alcohol treatment alcohol treatment center alcohol treatment facility alcoholic alcoholic behavior alcoholics Source Type: blogs
Abstract Sex is a critical factor in the diagnosis and development of a number of mental health disorders including autism, schizophrenia, depression, anxiety, Parkinson's disease, multiple sclerosis, anorexia nervosa and others; likely due to differences in sex steroid hormones and genetics. Recent evidence suggests that sex can also influence the complexity and diversity of microbes that we harbour in our gut; and reciprocally that our gut microbes can directly and indirectly influence sex steroid hormones and central gene activation. There is a growing emphasis on the role of gastrointestinal microbiota in the ...
Source: Frontiers in Neuroendocrinology - Category: Endocrinology Authors: Tags: Front Neuroendocrinol Source Type: research
One thing I shared with my wife Rachel about a year into our relationship was the time I suffered a nervous breakdown in graduate school. It would be an important moment in any relationship because I shared the time in my life when I was most vulnerable and at my weakest point. Did I technically suffer a nervous breakdown? I’m not sure, all I remember is the turning point came when I drove home late one night, collapsed on my kitchen floor and started crying uncontrollably. Up to that point, I had developed a quasi-schizophrenic outlook on life and could no longer bear the weight of the world-view I constructed. In p...
Source: Psych Central - Category: Psychiatry Authors: Tags: Borderline Personality Personal Stories Stigma Suicide Antidepressants Borderline Personality Disorder college Delusions Life Transition Nervous Breakdown Paranoia Psychosis Shame Stigmatization Source Type: news
Publication date: January 2020Source: Epilepsy &Behavior, Volume 102Author(s): Ciarán Campbell, Gianpiero L. Cavalleri, Norman DelantyAbstractThere is a long-documented epidemiological link between epilepsy and psychiatric disorders. People with epilepsy are at an increased risk for a variety of psychiatric illnesses, as are their family members, and people with epilepsy may experience psychiatric side effects because of their antiepileptic drugs (AEDs). In recent years, large-scale, collaborative international studies have begun to shed light on the role of genetic variation in both epilepsy and psychiatric ill...
Source: Epilepsy and Behavior - Category: Neurology Source Type: research
Abstract 1,25(OH)2D3 (1,25-dihydroxy-vitamin D3 = calcitriol) is a powerful regulator of mineral metabolism. The hormone increases calcium and phosphate plasma concentrations in part by stimulation of intestinal absorption and renal reabsorption of calcium and phosphate. It is primarily, but not exclusively, produced in the kidney. Renal 1,25(OH)2D3 formation is stimulated by calcium and phosphate deficiency and by parathyroid hormone which is up-regulated by hypocalcemia. 1,25(OH)2D3 formation is inhibited by fibroblast growth factor FGF23, which is up-regulated by phosphate excess and requires Klotho to become e...
Source: Neuro-Signals - Category: Neurology Authors: Tags: Neurosignals Source Type: research
Publication date: Available online 25 November 2019Source: NeuronAuthor(s): Zhaoqi Dong, Wenbing Chen, Chao Chen, Hongsheng Wang, Wanpeng Cui, Zhibing Tan, Heath Robinson, Nannan Gao, Bin Luo, Lei Zhang, Kai Zhao, Wen-Cheng Xiong, Lin MeiSummaryAutism spectrum disorders (ASD) are a group of neurodevelopmental disorders with symptoms including social deficits, anxiety, and communication difficulties. However, ASD pathogenic mechanisms are poorly understood. Mutations of CUL3, which encodes Cullin 3 (CUL3), a component of an E3 ligase complex, are thought of as risk factors for ASD and schizophrenia (SCZ). CUL3 is abundant i...
Source: Neuron - Category: Neuroscience Source Type: research
More News: Anxiety | Psychiatry | Schizophrenia | Study