Synthesis and Evaluation of a Novel Small-molecule Compound as an Anticancer Inhibitor of CD147.

CONCLUSION: Our results have clarified the tumor specificity of CD147 and its drug target characteristics. The biological profile of HA-08 suggests that this compound could be developed as a potential anticancer agent.
PMID: 31635683 [PubMed - in process]

Source: Biomedical and Environmental Sciences : BES - August 31, 2019 Category: Biomedical Science Authors: Fu ZG, Wang Y, Wang S, Shao D, Tian L, Li YX, Jiang JL, Chen ZN, Wen N Tags: Biomed Environ Sci Source Type: research