RUNX1 mutations promote leukemogenesis of myeloid malignancies in ASXL1-mutated leukemia

Additional sex combs-like 1 (ASXL1) mutations have been described in all forms of myeloid neoplasms including chronic myelomonocytic leukemia (CMML) and associated with inferior outcomes, yet the molecular pathog...

Source: Journal of Hematology and Oncology - October 22, 2019 Category: Hematology Authors: Rabindranath Bera, Ming-Chun Chiu, Ying-Jung Huang, Tung-Huei Lin, Ming-Chung Kuo and Lee-Yung Shih Tags: Research Source Type: research