Effect of phi29 polymerase-based multiple strand displacement whole genome amplification on the proportion in DNA mixtures

Multiple displacement amplification (MDA), an isothermal whole genome amplification method, has been applied extensively for its long amplification products and low bias. Because of preferential amplification and allelic drop-out with MDA when dealing with low template DNA (

Source: Forensic Science International: Genetics Supplement Series - October 22, 2019 Category: Forensic Medicine Authors: Qiang Zhu, Ting Fang, Yijun Zhou, Yiwen Yang, Yueyan Cao, Qiuyue Wang, Yuguo Huang, Yuhan Hu, Xiaogang Chen, Yufang Wang, Ji Zhang Source Type: research