Synthesis of defined mono-de-N-acetylated β-(1→6)-N-acetyl-D-glucosamine oligosaccharides to characterize PgaB hydrolase activity

Org. Biomol. Chem., 2019, Advance Article DOI: 10.1039/C9OB02079A, PaperAdam Forman, Roland Pfoh, Alexander Eddenden, P. Lynne Howell, Mark Nitz Mono-de-N-acetylated β-(1→6)-N-acetyl-D-glucosamine penta- and hepta-saccharides were obtained using a convergent synthesis. The site of de-N-acetylation drives the selectivity of hydrolysis by PgaB. To cite this article before page numbers are assigned, use the DOI form of citation above. The content of this RSS Feed (c) The Royal Society of Chemistry
Source: RSC - Organic and Biomolecular Chemistry - Category: Molecular Biology Authors: Source Type: research