SGLT2 inhibitors and urinary tract infections

Nature Reviews Endocrinology, Published online: 22 October 2019; doi:10.1038/s41574-019-0275-6Sodium–glucose cotransporter 2 (SGLT2) inhibitors are a fairly new class of treatment for diabetes mellitus. Some data suggest SGLT2 inhibitors are associated with a risk of severe urinary tract infections. However, meta-analyses of trials and a large population-based cohort study show no increased risk, which provides important reassurance for patients and prescribers.

Source: Nature Reviews Endocrinology - October 21, 2019 Category: Endocrinology Authors: John Wilding Source Type: research