Doctors can prescribe preventive pill for breast cancer

NICE recommends tamoxifen or raloxifene for up to five years for 'at-risk' women Related items from OnMedicaNew genetic test detects early breast cancerWomen may be offered drug to prevent breast cancerSERMs ward off common breast cancer over long termNICE draft rejects everolimus for advanced breast cancerSecrets of tamoxifen mechanism uncovered
Source: OnMedica Latest News - Category: UK Health Source Type: news

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Foods high in soluble fiber like oatmeal, nuts and beans were associated with reduced breast cancer incidence.
Source: NYT Health - Category: Consumer Health News Authors: Tags: Breast Cancer Diet and Nutrition Fiber (Dietary) Source Type: news
Publication date: Available online 5 April 2020Source: Seminars in Cancer BiologyAuthor(s): Emad A. Rakha, Fresia G. Pareja
Source: Seminars in Cancer Biology - Category: Cancer & Oncology Source Type: research
Publication date: Available online 4 April 2020Source: Seminars in Cancer BiologyAuthor(s): Michela Biancolella, Barbara Testa, Leila Baghernajad Salehi, Maria Rosaria D’Apice, Giuseppe Novelli
Source: Seminars in Cancer Biology - Category: Cancer & Oncology Source Type: research
AbstractPurpose of ReviewDetection of BRCA germline mutations (gBRCAm) impacts breast cancer medical treatment —according to differential sensitivity to cytotoxic chemotherapy and the activity of PARP inhibitors—and not only familial prevention. Guidelines for genetic testing—initially mainly based on familial history, age, and triple negative breast cancer (TNBC) subtype—currently are expanding in o rder to offer new therapeutic options.Recent FindingsIn the early setting, gBRCAm patients present a similar outcome as the non-carrier population with standard neoadjuvant chemotherapy, and the role of...
Source: Current Breast Cancer Reports - Category: Cancer & Oncology Source Type: research
The objective of the paper is to study cases of premalignant and malignant tumors, with a view to their imagistic identification confirmed in terms of histopathology, to highlight the accuracy of the imagistic examination as an important factor in the diagnosis and adaptation of an appropriate therapeutic attitude. The study was performed on a batch of 768 patients admitted to the Department of Surgery III, "Prof. Dr. Alexandru Trestioreanu" Institute of Oncology, Bucharest, Romania. The classical examined hypothesis is local examination, mammography, ultrasound, with its variations, and histopathological (HP) co...
Source: Romanian Journal of Morphology and Embryology - Category: General Medicine Tags: Rom J Morphol Embryol Source Type: research
Publication date: Available online 3 April 2020Source: Journal of Advanced ResearchAuthor(s): Auhood Nassar, Mohamed Abouelhoda, Osman Mansour, Samah A. Loutfy, Mohamed M. Hafez, M. Gomaa, Abeer Bahnassy, Amira Salah El-Din Youssef, Mai M. Lotfy, Hoda Ismail, Ola S. Ahmed, Amany Abd-Elhameed Abou-Bakr, Abdel-Rahman N. Zekri
Source: Journal of Advanced Research - Category: Research Source Type: research
AbstractGlypican-3 (GPC3) is a heparan sulfate proteoglycan that may function as a tumor suppressor in breast cancer (BC). To evaluate the prognostic value of GPC3 in BC, systematic analysis was performed in this study. To evaluate gene alteration during breast carcinogenesis, GPC3 expression was analyzed using the Oncomine, GENT, UALCAN, bcGenExMiner, and UCSC Xena databases. The prognostic role of GPC3 in BC was investigated using KM Plotter and PrognoScan databases. Promoter methylation status and heat map of GPC3 were determined using UALCAN and UCSC Xena. GPC3 expression was significantly downregulated in BC compared ...
Source: Network Modeling Analysis in Health Informatics and Bioinformatics - Category: Bioinformatics Source Type: research
AbstractPurposeEribulin methylate (eribulin) improved the overall survival (OS) of HER2-negative advanced breast cancer (HER2 −ABC) patients; however, the mechanism underlying the OS improvement has not been clarified. Several reports suggest that eribulin promotes antitumor immunity via tumor micro-environment conditioning. Recently, a maintained baseline lymphocyte count was proposed as predictive marker for eribulin t herapy in HER2−ABC patients; however, no associations with the OS have been noted. We retrospectively investigated the neutrophil-to-lymphocyte ratio and absolute lymphocyte count (ALC) in HER2...
Source: Breast Cancer Research and Treatment - Category: Cancer & Oncology Source Type: research
Connection between SOX7 Expression and Breast Cancer Prognosis. Med Sci Monit. 2020 Apr 02;26:e921510 Authors: Qin CX, Yang XQ, Zhan ZY Abstract BACKGROUND SOX7 exerts a repressing effect against tumors and imposes vital influences on malignancies. Our research discussed the importance of SOX7 in breast cancer prognoses. MATERIAL AND METHODS SOX7 mRNA expression in breast cancer tissues samples and matched adjacent normal controls of breast cancer patients was measured by quantitative real-time-polymerase chain reaction (qRT-PCR). The relationship of SOX7 with clinicopathological characteristics w...
Source: Medical Science Monitor - Category: Research Tags: Med Sci Monit Source Type: research
Publication date: Available online 3 April 2020Source: Food BioscienceAuthor(s): M.S. Taniya, Reshma MV, Shanimol PS, Gayatri Krishnan, Priya S
Source: Food Bioscience - Category: Food Science Source Type: research
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