Development and validation of a 21-plex str panel

Short tandem repeat (STR) analysis is the most common and informative type of DNA profiling widely used in paternity testing, missing persons ’ cases, and forensic applications. Several commercial kits based on STR technology were developed to meet current international standards, such as the European Standard Set (ESS) and the Combined DNA Index System (CODIS). Here, we report the development of the in-house STR panel ixMark PLUS that contains 21 markers: the 13 original CODIS STR loci with four non-overlapping loci from the expanded ESS, as well as SE33 and D6S1043, one Y-STR DYS391, and the sex-determining marker Amelogenin.
Source: Forensic Science International: Genetics Supplement Series - Category: Forensic Medicine Authors: Source Type: research