Occupational Use of Disinfectants May Up Risk for Developing COPD

FRIDAY, Oct. 18, 2019 -- Regular use of chemical disinfectants among nurses may be a risk factor for developing chronic obstructive pulmonary disease (COPD), according to a study published online Oct. 18 in JAMA Network Open. Orianne Dumas, Ph.D.,...
Source: Drugs.com - Pharma News - Category: Pharmaceuticals Source Type: news

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Publication date: Available online 25 January 2020Source: Redox BiologyAuthor(s): Marko Manevski, Thivanka Muthumalage, Dinesh Devadoss, Isaac K. Sundar, Qixin Wang, Kameshwar P. Singh, Hoshang J. Unwalla, Hitendra S. Chand, Irfan RahmanAbstractThe abnormal inflammatory responses due to the lung tissue damage and ineffective repair/resolution in response to the inhaled toxicants result in the pathological changes associated with chronic respiratory diseases. Investigation of such pathophysiological mechanisms provides the opportunity to develop the molecular phenotype-specific diagnostic assays and could help in designing ...
Source: Redox Biology - Category: Biology Source Type: research
Publication date: Available online 24 January 2020Source: Pulmonary Pharmacology &TherapeuticsAuthor(s): Monielle Sant’Ana Leal, Helena R. Souza, Lucas Possebon, Marinônio L. Cornélio, Yanira Riffo-Vasquez, Ana Paula Girol, Sonia M. OlianiAbstractChronic obstructive pulmonary disease (COPD) is related to smoking and anti-inflammatory therapy is indicated. Among the mediators with anti-inflammatory properties, we highlight piperlongumine (PL), an alkaloid/amide of Piper longum. Here we evaluated the PL administration on an experimental model of respiratory inflammation resulting from exposure to cigar...
Source: Pulmonary Pharmacology and Therapeutics - Category: Respiratory Medicine Source Type: research
Abstract The current qualitative study explored perceptions and experiences of chronic obstructive pulmonary disease (COPD) among Korean male older adults. Six older adults participated in a narrative group interview. Responses were analyzed to describe perceptions and experiences of COPD. Social stigma, blaming others and the environment, stress to bear alone, and adaptation and management emerged as relevant themes for adaptation to COPD. In relation to obstacles to healthy behaviors after adapting to COPD, emergent themes were adapting to symptoms, external environmental factors, alternative treatments, and ins...
Source: Journal of Gerontological Nursing - Category: Nursing Authors: Tags: J Gerontol Nurs Source Type: research
We present a case of acute hypercapnic exacerbation of COPD, intolerant to non-invasive ventilation, showing response and improvement on use of HFNC. This case highlights this potential mechanisms and prospects for the same. PMID: 31970968 [PubMed - in process]
Source: Monaldi Archives for Chest Disease - Category: Respiratory Medicine Tags: Monaldi Arch Chest Dis Source Type: research
Chronic lung disease is the fourth leading cause of death in the United States and third leading cause of death worldwide. Patients often live for years with reduced quality of life and significant distress related to symptoms, stigma, reduced functional capabilities, social isolation, and complicated self-management protocols. Evaluating the potential benefits of advanced life support and bronchoscopic or surgical interventions can be daunting, even for actively involved patients. The World Health Organization's GOLD Guidelines recommend pulmonary rehabilitation (PR), a 6- to 8-week course of exercise training, education,...
Source: Journal of Pain and Symptom Management - Category: Palliative Care Authors: Source Type: research
End-stage chronic obstructive disease (COPD) has a high level of symptom burden, requirement for long-term oxygen therapy and frequent exacerbations that require hospitalization. Research to date is limited regarding the delivery and impact of palliative care services in patients with end-stage COPD.
Source: Journal of Pain and Symptom Management - Category: Palliative Care Authors: Source Type: research
Inadequate palliative care knowledge and lack of clarity on nurses' roles in palliative care have been identified as barriers for appropriate palliative care services for COPD patients. Although nurses have been identified as key palliative care providers, knowledge gaps regarding palliative care delivery and inadequate communication training have acted as obstacles to addressing patient palliative care needs.
Source: Journal of Pain and Symptom Management - Category: Palliative Care Authors: Source Type: research
COPD is a leading cause of death;palliative care impact for this population is under recognized.
Source: Journal of Pain and Symptom Management - Category: Palliative Care Authors: Source Type: research
ConclusionWhile mixed associations between chitotriosidase activity and clinical outcomes were seen, chitotriosidase activity could be a predictor of future exacerbations in patients with a history of  ≥ 1 exacerbation in the past  12 months.
Source: Lung - Category: Respiratory Medicine Source Type: research
ConclusionsOur study analyzed the relationship of frailty and postoperative complications in patients with long bone fractures. Patients had increased likelihood of morbidity, independent of other comorbidities and demographic factors. The mFI may have a role as a simple, easy to use risk assessment tool in cases of orthopedic trauma.
Source: Journal of Clinical Orthopaedics and Trauma - Category: Orthopaedics Source Type: research
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