Pathogen identification by shotgun metagenomics of patients with necrotising soft-tissue infections.

CONCLUSIONS: SM showed a significantly better ability to detect a broader range of pathogens than TM and identify strict anaerobes than standard culture. Diabetic patients with NSTIs appeared to benefit most from shotgun metagenomics. Finally, our results suggest a bacterial continuum between macroscopically "healthy" non-necrotic areas and necrotic tissues. PMID: 31610037 [PubMed - as supplied by publisher]

https://www.ncbi.nlm.nih.gov/pubmed/31610037?dopt=Abstract

Source: The British Journal of Dermatology - October 13, 2019 Category: Dermatology Authors: Rodriguez C, Jary A, Hua C, Woerther PL, Bosc R, Desroches M, Sitterlé E, Gricourt G, De Prost N, Pawlotsky JM, Chosidow O, Sbidian E, Decousser JW, multidisciplinary necrotising fasciitis study group Tags: Br J Dermatol Source Type: research