Etchable SERS nanosensor for accurate pH and hydrogen peroxide sensing in living cells.

Etchable SERS nanosensor for accurate pH and hydrogen peroxide sensing in living cells.
Chem Commun (Camb). 2019 Oct 14;:
Authors: Bai L, Wang X, Zhang K, Tan X, Zhang Y, Xie W
Abstract
No methodology has been built to distinguish intracellular SERS nanosensors from cell outer membrane bound-ones. Here we propose a "turning off" strategy by combining etchable SERS nanosensors with a non-permeable etchant. The SERS signals outside the living cells can be rapidly removed, leaving only the internalized nanosensors for imaging and thereby allowing accurate intracellular pH and H2O2 sensing.
PMID: 31608348 [PubMed - as supplied by publisher]

Source: Chemical Communications - October 13, 2019 Category: Chemistry Authors: Bai L, Wang X, Zhang K, Tan X, Zhang Y, Xie W Tags: Chem Commun (Camb) Source Type: research