Globus pallidal deep brain stimulation for Tourette syndrome: Effects on cognitive function

In a double-blind randomized crossover trial, we previously established that bilateral deep brain stimulation of the anteromedial globus pallidus internus (GPiam-DBS) is effective in significantly reducing tic severity in patients with refractory Tourette syndrome (TS). Here, we report the effects of bilateral GPiam-DBS on cognitive function in 11 of the 13 patients who had participated in our double-blind cross-over trial of GPi-DBS.

Source: Parkinsonism and Related Disorders - October 13, 2019 Category: Neurology Authors: Davide Cappon, Mazda Beigi, Zinovia Kefalopoulou, Ludvic Zrinzo, Joseph Candelario, Catherine Milabo, Harith Akram, Viswas Dayal, Jonathan Hyam, Lewis Kass-Iliyya, Monty Silverdale, Julian Evans, Patricia Limousin, Marwan Hariz, Eileen Joyce, Thomas Folty Tags: Short communication Source Type: research