Identification and validation of microRNA profiles in fecal samples for detection of colorectal cancer

Screening for colorectal cancer (CRC) is effective in average-risk population. The most extended strategy in organized programs involves the fecal immunochemical test, which is limited by low sensitivity for detection of advanced adenomas (AAs). We aimed to identify microRNA (miRNA) signatures in fecal samples that identify patients with AAs or CRC and might be used in non-invasive screening.

Source: Gastroenterology - October 13, 2019 Category: Gastroenterology Authors: Saray Duran-Sanchon, Lorena Moreno, Josep M. Aug é, Miquel Serra-Burriel, Míriam Cuatrecasas, Leticia Moreira, Agatha Martín, Anna Serradesanferm, Àngels Pozo, Rosa Costa, Antonio Lacy, Maria Pellisé, Juan José Lozano, Meritxell Gironella, Antoni Ca Source Type: research