Phospholipase-C γ1 Signaling Protein Down-Regulation by Oligoclonal-VHHs based Immuno-Liposome: A Potent Metastasis Deterrent in HER2 Positive Breast Cancer Cells.

Conclusion: PLCγ1 protein levels did indeed decrease after treatment with immuno-liposome form of compounds in both two tested cell lines, verifying the inhibition ability of them. Moreover, an elevated antibody activity is associated with liposomes conjugation suggesting that immuno-liposome may be a potential target for enhancing the antibody activity. PMID: 31606964 [PubMed]

https://www.ncbi.nlm.nih.gov/pubmed/31606964?dopt=Abstract

Source: Cancer Control - October 14, 2019 Category: Cancer & Oncology Authors: Asadpour O, Rahbarizadeh F Tags: Cell J Source Type: research