Iodine-Catalyzed Guanylation of Amines with N,N ′-Di-Boc-thiourea

Org. Biomol. Chem., 2019, Accepted Manuscript DOI: 10.1039/C9OB02014D, CommunicationBing-Ke Ning, Hao-Jie Rong, Cui-Feng Yang, Tao Chen, Ze-Gang Xu, Tian-Duo Su, Yong-Qiang Wang Herein we report that iodine-catalyzed guanylation of primary amines can be accomplished with N,N ′-di-Boc-thiourea and TBHP to afford the corresponding guanidines in 40–99% yields. Oxidation of the HI byproduct by... The content of this RSS Feed (c) The Royal Society of Chemistry
Source: RSC - Organic and Biomolecular Chemistry - Category: Molecular Biology Authors: Source Type: research