Rat Bites in the Diabetic Foot: Clinical Clues
We describe and analyse the features of rat bites in 2 patients with diabetic neuropathic feet and highlight 8 clinical features that should raise suspicion and alert the clinician to this possibility.
Condition: Diabetic Foot Ulcer Intervention: Device: Noraxon myoRESEARCH™ Software Gait Analysis Evaluation and Orthotic Sponsor: Johns Hopkins University Not yet recruiting
Resumo Contexto As infec ções profundas de extremidades representam um desafio para o salvamento de membro dos pacientes. Objetivos Investigar se existe concordância entre as culturas de osso e tecido profundo em pacientes com lesões tróficas de extremidades. Métodos Foi realizado um estudo retrospectivo incluindo 5 4 pacientes com lesões tróficas profundas de extremidades internados, no Complexo Hospitalar Universitário Professor Edgard Santos, Salvador (BA), Brasil. Foram incluídos todos os pacientes que realizaram culturas de lesões trófi...
Might a novel acellular fish skin graft offer a new effective treatment option for diabetic foot ulcers?Wounds
Dysregulation of glucose homeostasis and elevated glucose levels are central etiologies of diabetes, a medical condition commonly encountered . WHO has projected that the incidence of diabetes will continue to rise around the globe . An important complication associated with diabetes is poor wound healing that may lead to ulceration, infection, and ultimately amputation . Clearly, understanding the mechanisms responsible for poor diabetic wound healing is an important public health issue that needs to be addressed.
AbstractPurpose of ReviewCommercialization of an automated epidermal harvesting device (CelluTome ™, Kinetic Concepts Inc., San Antonio, TX) in the last 6 years has led to numerous publications describing a growing number of clinical applications. The current article reviews this literature while summarizing outcomes.Recent FindingsA total of 20 published reports including 284 automated graft recipients have been published. Complete reepithelialization occurs in 50 –92% of recipient sites, often within 4–18 weeks of graft placement. Donor sites heal without scarring within 1–2 weeks.S...
This study investigates the effect of high glucose and hypoxic conditions on TLR4 activation and signalling in vitro and in vivo.
ConclusionOur meta-analysis indicated that ischemic ulcer, ulcer size, ulcer grade, osteomyelitis, previous antibiotic therapy and previous hospitalization were associated with MDRO infection in patients with diabetic foot ulcers.
Conclusion: HSAM increased frequency and probability of wound closure in DFUs versus SOC. PMID: 31691579 [PubMed - as supplied by publisher]
In conclusion, miRNA-497, with its down-regulation activity for pro-inflammatory cytokines, is proposed as a potential therapeutic agent for diabetic wound healing. PMID: 31707336 [PubMed - as supplied by publisher]
Conditions: Diabetic Foot; Hammer Toe; Mallet Toe; Claw Toe Intervention: Procedure: Tenotomy(cutting) of flexor tendons is performed with needle Sponsors: Steno Diabetes Center Copenhagen; Bispebjerg Hospital; Hillerod Hospital, Denmark Not yet recruiting