A self-assembled Ru-Pt metallacage as a lysosome-targeting photosensitizer for 2-photon photodynamic therapy [Chemistry]

Photodynamic therapy (PDT) is a treatment procedure that relies on cytotoxic reactive oxygen species (ROS) generated by the light activation of a photosensitizer. The photophysical and biological properties of photosensitizers are vital for the therapeutic outcome of PDT. In this work a 2D rhomboidal metallacycle and a 3D octahedral metallacage...

Source: Proceedings of the National Academy of Sciences - October 7, 2019 Category: Science Authors: Zhixuan Zhou, Jiangping Liu, Juanjuan Huang, Thomas W. Rees, Yiliang Wang, Heng Wang, Xiaopeng Li, Hui Chao, Peter J. Stang Tags: Physical Sciences Source Type: research