Cancer, the foods you love and the truth about your Sunday roast beef

WHO data shows the risk of colorectal cancer is 1.18 times higher if you eat 50g of processed red meat per day. But the risk of any cancer is 40 times higher if you smoke - or 70 times higher if you drink as well.
Source: the Mail online | Health - Category: Consumer Health News Source Type: news

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Date: Tuesday, 11 12, 2019; Speaker: Meira Epplein, PhD, Associate Professor in Population Health Sciences, Associate Prof in Medicine, Department of Medicine, Duke University School of Medicine ;
Source: NIH Calendar of Events - Category: American Health Source Type: events
Conclusions: The results indicate that a possible mechanism behind an anastomotic leakage is an impaired circulation and thus insufficient saturation to the small intestine peroperatively. This develops into an inflammation both intraperitoneally and intravenously, which, if not reversed, spread within the gastrointestinal tract .The colorectal anastomosis is the most vulnerable part of the gastrointestinal tract postoperatively and hypoxia and inflammation may occur there, and an anastomosis leakage will be the consequence. PMID: 31630578 [PubMed - as supplied by publisher]
Source: Scandinavian Journal of Gastroenterology - Category: Gastroenterology Tags: Scand J Gastroenterol Source Type: research
Publication date: Available online 22 October 2019Source: Preventive MedicineAuthor(s): Wendy E. Barrington, Amy DeGroff, Stephanie Melillo, Thuy Vu, Allison Cole, Cam Escoffery, Natoshia Askelson, Laura Seegmiller, Sarah Koopman Gonzalez, Peggy HannonAbstractFew data are available on patient navigators (PNs) across diverse roles and organizational settings that could inform optimization of patient navigation models for cancer prevention. The National Breast and Cervical Cancer Early Detection Program (NBCCEDP) and the Colorectal Cancer and Control Program (CRCCP) are two federally-funded screening programs that support cl...
Source: Preventive Medicine - Category: International Medicine & Public Health Source Type: research
Hi, i’m about to finish 1st year hem/onc fellowship in a mid-tier academic program. Also have a PhD in cancer biology with publications (in colon cancer). No visa issue. I’m having a hard time in choosing my career path. The things that I value most is lifestyle and pay. I have 2 young children to support. So far, I know I like treating solid tumors, but do not have a specific disease that dominate my interests. Our program is clinically heavy in 1st year, so far I did not do any meaning... Hem/onc fellow, how to decide on career path
Source: Student Doctor Network - Category: Universities & Medical Training Authors: Tags: Hematology / Oncology Source Type: forums
There were 1.8million new cases of bowel cancer in 2017, up by 9.5 per cent over the last 27 years. Figures show 52,331 people were diagnosed with the disease in 2017 and 209,237 in the US.
Source: the Mail online | Health - Category: Consumer Health News Source Type: news
AbstractDiffusing alpha-emitters radiation therapy (DaRT) is the only known method for treating solid tumors with highly destructive alpha radiation. More importantly, as a monotherapy, DaRT has been shown to induce a systemic antitumor immune response following tumor ablation. Here, immunomodulatory strategies to boost the antitumor immune response induced by DaRT, and the response specificity, were investigated in the colon cancer CT26 mouse model. Local treatment prior to DaRT,  with the TLR3 agonist poly I:C, was sufficient to inhibit tumor growth relative to poly I:C or DaRT alone. DaRT used in combination with t...
Source: Cancer Immunology, Immunotherapy - Category: Cancer & Oncology Source Type: research
ConclusionsTreatment of anal cancer results in low rates of salvage surgery and permanent ostomies, when therapy was determined by a multidisciplinary team following national and international guidelines.
Source: International Journal of Colorectal Disease - Category: Gastroenterology Source Type: research
Eupafolin is the main bioactive component extracted from the traditional Chinese medicine Ay Tsao (Artemisia vulgaris L.), and its anti-tumor activity has had been studied in previous researches. T-LAK cell-originated protein kinase (TOPK) belongs to serine/threonine protein kinase and is highly expressed in several cancer cells and tissues, such as colon cancer, lung cancer, esophagus cancer, and so on. Therefore, it was recognized as an important target for treating tumors. Nowadays, we found that eupafolin suppressed TOPK activities at the first time in vitro and in vivo. The cells study indicated that eupafolin suppres...
Source: Frontiers in Pharmacology - Category: Drugs & Pharmacology Source Type: research
Background and Objective: Hepatocyte nuclear factor 3β (HNF3β) is a key transcription factor in the development of the gastrointestinal tract. However, only few studies have examined its' expression, function and potential clinical significance in colorectal cancer tumorigenesis and progression.Methods: HNF3β expression in colorectal cancer tissue samples of 174 patients was assessed by immunohistochemistry. The results were analyzed with respect to patients' clinicopathological characteristics and survival. Following the in vitro cell transfection, MTT, wound healing, and Transwell assays were used to test ...
Source: Frontiers in Oncology - Category: Cancer & Oncology Source Type: research
A new clinical practice guideline challenges the validity of routine colorectal cancer screening beneath a certain risk threshold. Dr David Johnson advises caution about adopting its recommendations.Medscape Gastroenterology
Source: Medscape Gastroenterology Headlines - Category: Gastroenterology Tags: Gastroenterology Commentary Source Type: news
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