Identifying Similarities and Disparities between DNA Copy Number Changes in Cancer and Matched Blood Samples.

Conclusions: The results showed that a few chromosomes have a large number of MICs exceeding a high threshold. These locations can potentially be used to identify early indicators of NSCLC. In contrast, second group of chromosomes have several locations with small MICs which are potential candidates to develop biomarkers for discriminating cancer from the matched blood sample. Moreover, there is a third group of chromosomes with a large number of MICs exceeding a high threshold and a large set of MICs below a low threshold. These locations can help with both finding early indicators of cancer and developing biomarkers for discriminating cancer from non-involved tissue. PMID: 31584296 [PubMed - as supplied by publisher]
Source: Cancer Investigation - Category: Cancer & Oncology Tags: Cancer Invest Source Type: research