Oral and cutaneous manifestations of langerhans cell histiocytosis: report of two cases

Publication date: Available online 21 September 2019Source: Journal of Oral and Maxillofacial Surgery, Medicine, and PathologyAuthor(s): Jefferson da Rocha Tenório, Camilla Vieira Esteves, Daniele Heguedusch, Suzana Cantanhede Orsini Machado de Sousa, Celso Augusto Lemos-JúniorAbstractLangerhans cell histiocytosis (LCH) is a rare myeloid proliferative disorder characterized by abnormal proliferation of Langerhans cells, which can produce focal or systemic manifestations. Oral mucosa lesions of LCH are a diagnostic challenge, because of their destructive osteolytic character that could simulate other types of diseases in this region. Presently we report a regular case of LCH in a 12-year-old boy and an unusual one that presented concomitantly oral and skin lesions, in a 67-year-old woman. The two reported cases presented two different manifestations of this condition in different ages, showing the difficulty in general dentistry, mainly in pediatric and geriatric clinic that should considered LCH as differential diagnosis for the oral mucosa lesions with periodontal impairment.
Source: Journal of Oral and Maxillofacial Surgery, Medicine, and Pathology - Category: ENT & OMF Source Type: research