Molecular allergen profiling of dual mite sensitization in severe allergic rhinitis.
CONCLUSIONS: Although the combination panel of the commercially available major allergens Der p 1, Der p 2 and Der p 23, identified more than 90% of the D. pteronyssinus allergic patients, Blo t 5 showed a very limited performance in those sensitized to B. tropicalis. Improvements in CRD and further research concerning the prevalence and clinical relevance of serodominant allergens are needed to achieve a genuine molecular diagnosis along with a patient-centred mite-allergy specific immunotherapy.
PMID: 31530505 [PubMed - as supplied by publisher]
Source: Journal of Investigational Allergology and Clinical Immunology - Category: Allergy & Immunology Authors: González-Pérez R, Pineda F, Poza-Guedes P, Castillo M, Matheu V, Sánchez-Machín I Tags: J Investig Allergol Clin Immunol Source Type: research