Inmunorreacci ón de la infección por el virus de Zika en retina de ratones.
[Inmunorreacción de la infección por el virus de Zika en retina de ratones]. Biomedica. 2019 Aug 01;39(Supl. 2):8-10 Authors: Rivera J, Rengifo AC, Santamaría G, Corchuelo S, Álvarez-Díaz D, Parra EA, Naizaque J, Monroy-Gómez J, Torres-Fernández O PMID: 31529828 [PubMed - in process]
This study provides valuable data on sex-specific expression of protein-coding genes and lncRNAs in adult Ae. albopictus, which will guide further studies aimed at understanding sex development and determination mechanisms in this species.
nah Kuper We aimed to explore the engagement of fathers in a community-based group intervention (Juntos) for children with congenital Zika syndrome (CZS) and their caregivers in Brazil. Six Juntos groups were facilitated from August 2017 to May 2018. We conducted a qualitative study to evaluate the feasibility and acceptability of the intervention for fathers of children with CZS. Methods included participant observation, focus group discussions, and semi-structured interviews of fathers with a child enrolled in the program. Data collected were transcribed, coded and thematically analyzed to explore father preference f...
Review looks at the body of information that was acquired during the pandemic and discussed the epidemiologic trends, current knowledge about the transmission and natural history of Zika virus infection and its sequelae, and the principles of diagnosis and clinical management.
ACS NanoDOI: 10.1021/acsnano.9b02807
Contributors : Nandan S Gokhale ; Alexa B McIntyre ; Melissa D Mattocks ; Christopher L Holley ; Helen M Lazear ; Christopher E Mason ; Stacy M HornerSeries Type : Expression profiling by high throughput sequencingOrganism : Homo sapiensThe RNA modification N6-methyladenosine (m6A) can modulate mRNA fate and thus affect many biological processes. We analyzed m6A modification across the transcriptome following infection by dengue virus (DENV), Zika virus (ZIKV), West Nile virus (WNV), and hepatitis C virus (HCV). We found that infection by these viruses in the Flaviviridae family alters m6A modification of specific cellular...
Journal of Natural ProductsDOI: 10.1021/acs.jnatprod.9b00251
Conclusions and significanceAlthough IRM should be a fixture of all vector control programs, it is currently often absent from the strategic plans to control mosquito-borne diseases, especially arboviruses. Experiences from other public health disease vectors and agricultural pests underscore the need for urgent action in implementing IRM for invasiveAedes mosquitoes. Based on a plan developed for malaria vectors, here we propose some key activities to establish a global plan for IRM inAedes spp.
by Andrew J. Monaghan, Rebecca J. Eisen, Lars Eisen, Janet McAllister, Harry M. Savage, John-Paul Mutebi, Michael A. JohanssonAedes (Stegomyia) aegypti (L.) andAe.(Stegomyia) albopictus (Skuse) mosquitoes can transmit dengue, chikungunya, yellow fever, and Zika viruses. Limited surveillance has led to uncertainty regarding the geographic ranges of these vectors globally, and particularly in regions at the present-day margins of habitat suitability such as the contiguous United States. Empirical habitat suitability models based on environmental conditions can augment surveillance gaps to describe the estimated potential spe...
A new review of research on the Zika virus since 2016 finds there is still much scientists don't understand about the pandemic — including when another may strike. (Image credit: Mario Tama/Getty Images)
Authors: Cho JH, Bassit LC, Amblard F, Schinazi RF Abstract Novel 7-trifluoromethyl-7-deazapurine ribonucleoside analogs (13a-c) and their Protides (15a-c) were successfully synthesized from ribolactol or 1-α-bromo-ribose derivatives using Silyl-Hilbert-Johnson or nucleobase-anion substitution reactions followed by key aromatic trifluoromethyl substitution. Newly prepared compounds were evaluated against a panel of RNA viruses, including HCV, Ebola or Zika viruses. PMID: 31588837 [PubMed - as supplied by publisher]