A dimeric bicyclic RGD ligand displays enhanced integrin binding affinity and strong biological effects on U-373 MG glioblastoma cells

Org. Biomol. Chem., 2019, Accepted Manuscript DOI: 10.1039/C9OB01811E, PaperGiovanni Sacco, Alberto Dal Corso, Daniela Arosio, Laura Belvisi, Mayra Paolillo, Luca Pignataro, Cesare Gennari A C2-symmetric bicyclic peptide bearing two RGD motifs was developed as dimeric ligand, and displayed enhanced inhibition of ECM protein binding to purified integrin receptors as compared to monomeric RGD... The content of this RSS Feed (c) The Royal Society of Chemistry
Source: RSC - Organic and Biomolecular Chemistry - Category: Molecular Biology Authors: Source Type: research