NIDDK Administrative Speaker Series: Identifying the Genetic Basis of Obesity and Type 2 Diabetes in Southwest American Indians

2019 NIDDK Administrative Speaker Series The series is an opportunity for NIDDK staff to learn about the important science NIDDK conducts and supports. It is also an excellent way to inspire our administrative staff, as it allows them a chance to hear and see how their roles contribute to and/or impact the work of the scientists.Air date: 10/9/2019 1:00:00 PM
Source: Videocast - All Events - Category: General Medicine Tags: Upcoming Events Source Type: video

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Publication date: January 2020Source: LWT, Volume 118Author(s): Vítor Spínola, Eulogio J. Llorent-Martínez, Paula C. CastilhoAbstractIn this work, we report the in vitro inhibitory potential of Rumex maderensis methanolic extracts (leaves, flowers, and stems) towards key digestive enzymes linked to type-2 diabetes and obesity (α-amylase, α-glucosidase, pancreatic lipase). The inhibitory activity towards aldose reductase and glycation of bovine serum albumin (BSA) is also reported; in these latter assays, the effect of simulated digestion on the bioactivities was evaluated. The inhibitory ac...
Source: LWT Food Science and Technology - Category: Food Science Source Type: research
Evaluating stress levels over time and intervening when high perceived stress persists might reduce hypertension risk Related items fromOnMedica Should we recognise obesity as a disease? Type 2 diabetes in 10 times more young people than realised Pharmacists could offer high-dose statins direct to patients WHO dietary fat guidance fails to consider crucial evidence Plant-based diet linked to lower risk of heart failure
Source: OnMedica Latest News - Category: UK Health Source Type: news
The evidence is clear. Bariatric surgery provides wide-ranging benefits to adolescents with obesity and type 2 diabetes, says Dr Louise Baur.Medscape Diabetes &Endocrinology
Source: Medscape Diabetes Headlines - Category: Endocrinology Tags: Diabetes & Endocrinology Commentary Source Type: news
Conditions:   Obesity;   Diabetes Mellitus, Type 2;   Insulin Resistance Intervention:   Other: Methylation status Sponsor:   University of Arizona Recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
Condition:   Childhood Obesity Intervention:   Behavioral: Evaluation of whiteboard videos Sponsors:   The Hospital for Sick Children;   University of Ottawa Not yet recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
Conditions:   Obesity;   Diabetes Mellitus, Type 2;   Insulin Resistance Intervention:   Other: Methylation status Sponsor:   University of Arizona Recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
Condition:   Childhood Obesity Intervention:   Behavioral: Evaluation of whiteboard videos Sponsors:   The Hospital for Sick Children;   University of Ottawa Not yet recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
Chronic illnesses like obesity, type 2 diabetes (T2D) and cardiovascular diseases, are worldwide major causes of morbidity and mortality. These pathological conditions involve interactions between environmenta...
Source: Lipids in Health and Disease - Category: Lipidology Authors: Tags: Review Source Type: research
The Metabolic Syndrome may be tentatively defined as the clustering of several metabolic risk factors in the same individual. A progressively higher number of children and adolescents is affected by this syndrome worldwide, mainly as a consequence of the constant increase of the prevalence of obesity and sedentary habits. As obesity, the chance that the metabolic syndrome traks into adulthood is high. Moreover, the evidence of an association between the duration of the exposition to metabolic risk factors and morbidity and mortality justifies early treatment and prevention of the metabolic syndrome in both children and ado...
Source: Frontiers in Endocrinology - Category: Endocrinology Source Type: research
CONCLUSION: GLP-1 RA therapy represents an important add-on therapy option for achieving decreased insulin doses, weight loss, and modest improvements in HbA1c levels without significantly increasing hypoglycemia risk in patients with T1DM. Patients who have detectable C-peptide and/or are overweight or cannot achieve glycemic goals without hypoglycemia have been found to benefit the most from GLP-1 RA therapy. Further studies are warranted to evaluate these agents' potential impact on clinical outcomes such as microvascular and macrovascular complications. PMID: 31612934 [PubMed - in process]
Source: American Journal of Health-System Pharmacy : AJHP - Category: Drugs & Pharmacology Authors: Tags: Am J Health Syst Pharm Source Type: research
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