Effects of Family History on Relative and Absolute Risks for Colorectal Cancer: a Systematic Review and Meta-Analysis

Guidelines recommend individuals with familial colorectal cancer (FCC) to undergo colonoscopy surveillance instead of average-risk screening. However, these recommendations vary widely. To substantiate appropriate surveillance strategies, precise and valid evidence-based risk estimates are needed for individuals with a family history of colorectal cancer (CRC).

Source: Clinical Gastroenterology and Hepatology - September 12, 2019 Category: Gastroenterology Authors: Victorine H. Roos, Carolina Mangas-Sanjuan, Mar Rodriguez-Girondo, Lucia Medina Prado, Ewout W. Steyerberg, Patrick M.M. Bossuyt, Evelien Dekker, Rodrigo Jover, Monique E. van Leerdam Source Type: research