Study of the variability of rutin, vitexin, hyperoside, quercetin in "Crataegi folium cum flore" of Hawthorn (Crataegus L.) species from Russian flora

Publication date: Available online 9 September 2019Source: Journal of Applied Research on Medicinal and Aromatic PlantsAuthor(s): Valentina A. Sagaradze, Elena Y. Babaeva, Roman A. Ufimov, Nikolai A. Trusov, Elena I. KalenikovaAbstractThe genus Crataegus L. involving several hundred species is distributed worldwide. Nevertheless, only a few species are included in Pharmacopoeias and used for medical purpose. As Hawthorn plants usually grow in small groups, the harvesting of raw material is complicated. The search of species suitable for further inclusion in Pharmacopoeia may facilitate this task. Thus, a comparative analysis of the flavonoid content in herbal raw material ("folium cum flore") from Crataegus species growing in Russia was performed. We compared Crataegus section (7 species) widely distributed in Europe, South-Western and Central Asia and often used for medical purpose with Sanguineae section (8 species) growing in the Asian region of the Russian Federation. Total flavonoid (expressed as hyperoside) yields of the 15 Crataegus spp. investigated by UV-vis spectrophotometry ranged from 12.1 ± 1.1 (C. maximowiczii) to 22.1 ± 0.9 mg/g (C. ambigua), average – 16.5 mg/g. Assays for rutin, vitexin, hyperoside and quercetin were performed using the HPLC-UV method. Hyperoside was the predominant compound in all species except C. nigra and ranged from 1.55 (C. nigra) to 12.59 mg/g (C. monogyna), median – 4.47 mg/g. Rutin ranged from 0.35 to 5.37 mg/...
Source: Journal of Applied Research on Medicinal and Aromatic Plants - Category: Complementary Medicine Source Type: research