Enhancer variants associated with Alzheimer ’s disease affect gene expression via chromatin looping

Genome-wide association studies (GWASs) have identified single-nucleotide polymorphisms (SNPs) that may be genetic factors underlying Alzheimer ’s disease (AD). However, how these AD-associated SNPs (AD SNPs) c...

Source: BMC Medical Genomics - September 9, 2019 Category: Genetics & Stem Cells Authors: Masataka Kikuchi, Norikazu Hara, Mai Hasegawa, Akinori Miyashita, Ryozo Kuwano, Takeshi Ikeuchi and Akihiro Nakaya Tags: Research article Source Type: research