Synthesis Of 1,4,5-Trisubstituted 1,2,3-Triazoles Amicable For Automation.
Synthesis Of 1,4,5-Trisubstituted 1,2,3-Triazoles Amicable For Automation.
Comb Chem High Throughput Screen. 2013 Apr 10;
Authors: Kavitha M, Mahipal B, Mainkar PS, Chandrasekhar S
Abstract
A three-component 3+2 cycloaddition reaction followed by Suzuki coupling reaction were carried out to synthesize a library of compounds using automation (parallel synthesizer). Scaffolds that are unexplored in literature were used for the synthesis of library. The iodo-triazoles formed by 3+2 cycloaddition reaction were coupled with boronic acids to get tri-substituted triazoles.
PMID: 23597250 [PubMed - as supplied by publisher]
Source: Combinatorial Chemistry and High Throughput Screening - Category: Chemistry Authors: Kavitha M, Mahipal B, Mainkar PS, Chandrasekhar S Tags: Comb Chem High Throughput Screen Source Type: research
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